HIV infection in Eastern and Southern Africa: Highest burden, largest challenges, greatest potential

Background: The burden of HIV is especially concerning for Eastern and Southern Africa (ESA), as despite expansion of test-and-treat programmes, this region continues to experience significant challenges resulting from high rates of morbidity, mortality and new infections. Hard-won lessons from prog...

Full description

Bibliographic Details
Main Authors: Erica Parker, Melinda A. Judge, Eusebio Macete, Tacilta Nhampossa, Jienchi Dorward, Denise C. Langa, Caroline De Schacht, Aleny Couto, Paula Vaz, Marco Vitoria, Lucas Molfino, Rachel T. Idowu, Nilesh Bhatt, Denise Naniche, Peter N. Le Souëf
Format: Article
Language:English
Published: AOSIS 2021-05-01
Series:Southern African Journal of HIV Medicine
Subjects:
Online Access:https://sajhivmed.org.za/index.php/hivmed/article/view/1237
_version_ 1811231234600206336
author Erica Parker
Melinda A. Judge
Eusebio Macete
Tacilta Nhampossa
Jienchi Dorward
Denise C. Langa
Caroline De Schacht
Aleny Couto
Paula Vaz
Marco Vitoria
Lucas Molfino
Rachel T. Idowu
Nilesh Bhatt
Denise Naniche
Peter N. Le Souëf
author_facet Erica Parker
Melinda A. Judge
Eusebio Macete
Tacilta Nhampossa
Jienchi Dorward
Denise C. Langa
Caroline De Schacht
Aleny Couto
Paula Vaz
Marco Vitoria
Lucas Molfino
Rachel T. Idowu
Nilesh Bhatt
Denise Naniche
Peter N. Le Souëf
author_sort Erica Parker
collection DOAJ
description Background: The burden of HIV is especially concerning for Eastern and Southern Africa (ESA), as despite expansion of test-and-treat programmes, this region continues to experience significant challenges resulting from high rates of morbidity, mortality and new infections. Hard-won lessons from programmes on the ground in ESA should be shared. Objectives: This report summarises relevant evidence and regional experts’ recommendations regarding challenges specific to ESA. Method: This commentary includes an in-depth review of relevant literature, progress against global goals and consensus opinion from experts. Results: Recommendations include priorities for essential research (surveillance data collection, key and vulnerable population education and testing, in-country testing trials and evidence-based support services to improve retention in care) as well as research that can accelerate progress towards the prevention of new infections and achieving ambitious global goals in ESA. Conclusion: The elimination of HIV in ESA will require continued investment, commitment to evidence-based programmes and persistence. Local research is critical to ensuring that responses in ESA are targeted, efficient and evaluated.
first_indexed 2024-04-12T10:41:58Z
format Article
id doaj.art-c8a18ab86488470caecb5959d4e58037
institution Directory Open Access Journal
issn 1608-9693
2078-6751
language English
last_indexed 2024-04-12T10:41:58Z
publishDate 2021-05-01
publisher AOSIS
record_format Article
series Southern African Journal of HIV Medicine
spelling doaj.art-c8a18ab86488470caecb5959d4e580372022-12-22T03:36:35ZengAOSISSouthern African Journal of HIV Medicine1608-96932078-67512021-05-01221e1e810.4102/sajhivmed.v22i1.1237752HIV infection in Eastern and Southern Africa: Highest burden, largest challenges, greatest potentialErica Parker0Melinda A. Judge1Eusebio Macete2Tacilta Nhampossa3Jienchi Dorward4Denise C. Langa5Caroline De Schacht6Aleny Couto7Paula Vaz8Marco Vitoria9Lucas Molfino10Rachel T. Idowu11Nilesh Bhatt12Denise Naniche13Peter N. Le Souëf14Faculty of Health and Medical Sciences, The University of Western Australia, PerthFaculty of Health and Medical Sciences, The University of Western Australia, PerthManhiça Health Research Centre, ManhiçaManhiça Health Research Centre, ManhiçaNuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, United Kingdom; and, Centre for the AIDS Programme of Research in South Africa (CAPRISA), University of KwaZulu-Natal, Durban, South AfricaDepartment of Surveillance, Instituto Nacional de Saúde, MaputoFriends in Global Health, MaputoNational STI, HIV/AIDS Programme, Ministry of Health, MaputoFundaçao Ariel Glaser contra o SIDA pediátrico, MaputoDepartment of HIV/AIDS, World Health Organization, GenevaMédecins Sans Frontières, MaputoCenter for Global Health, Centers for Disease Control and Prevention, MaputoElizabeth Glaser Pediatric AIDS Foundation, MaputoManhiça Health Research Centre, Manhiça, Mozambique; and, Barcelona Institute for Global Health (ISGlobal), SpainFaculty of Health and Medical Sciences, The University of Western Australia, PerthBackground: The burden of HIV is especially concerning for Eastern and Southern Africa (ESA), as despite expansion of test-and-treat programmes, this region continues to experience significant challenges resulting from high rates of morbidity, mortality and new infections. Hard-won lessons from programmes on the ground in ESA should be shared. Objectives: This report summarises relevant evidence and regional experts’ recommendations regarding challenges specific to ESA. Method: This commentary includes an in-depth review of relevant literature, progress against global goals and consensus opinion from experts. Results: Recommendations include priorities for essential research (surveillance data collection, key and vulnerable population education and testing, in-country testing trials and evidence-based support services to improve retention in care) as well as research that can accelerate progress towards the prevention of new infections and achieving ambitious global goals in ESA. Conclusion: The elimination of HIV in ESA will require continued investment, commitment to evidence-based programmes and persistence. Local research is critical to ensuring that responses in ESA are targeted, efficient and evaluated.https://sajhivmed.org.za/index.php/hivmed/article/view/1237hiv epidemiologypublic healthrisk factorsvulnerable populationsprevention and controlearly diagnosis
spellingShingle Erica Parker
Melinda A. Judge
Eusebio Macete
Tacilta Nhampossa
Jienchi Dorward
Denise C. Langa
Caroline De Schacht
Aleny Couto
Paula Vaz
Marco Vitoria
Lucas Molfino
Rachel T. Idowu
Nilesh Bhatt
Denise Naniche
Peter N. Le Souëf
HIV infection in Eastern and Southern Africa: Highest burden, largest challenges, greatest potential
Southern African Journal of HIV Medicine
hiv epidemiology
public health
risk factors
vulnerable populations
prevention and control
early diagnosis
title HIV infection in Eastern and Southern Africa: Highest burden, largest challenges, greatest potential
title_full HIV infection in Eastern and Southern Africa: Highest burden, largest challenges, greatest potential
title_fullStr HIV infection in Eastern and Southern Africa: Highest burden, largest challenges, greatest potential
title_full_unstemmed HIV infection in Eastern and Southern Africa: Highest burden, largest challenges, greatest potential
title_short HIV infection in Eastern and Southern Africa: Highest burden, largest challenges, greatest potential
title_sort hiv infection in eastern and southern africa highest burden largest challenges greatest potential
topic hiv epidemiology
public health
risk factors
vulnerable populations
prevention and control
early diagnosis
url https://sajhivmed.org.za/index.php/hivmed/article/view/1237
work_keys_str_mv AT ericaparker hivinfectionineasternandsouthernafricahighestburdenlargestchallengesgreatestpotential
AT melindaajudge hivinfectionineasternandsouthernafricahighestburdenlargestchallengesgreatestpotential
AT eusebiomacete hivinfectionineasternandsouthernafricahighestburdenlargestchallengesgreatestpotential
AT taciltanhampossa hivinfectionineasternandsouthernafricahighestburdenlargestchallengesgreatestpotential
AT jienchidorward hivinfectionineasternandsouthernafricahighestburdenlargestchallengesgreatestpotential
AT deniseclanga hivinfectionineasternandsouthernafricahighestburdenlargestchallengesgreatestpotential
AT carolinedeschacht hivinfectionineasternandsouthernafricahighestburdenlargestchallengesgreatestpotential
AT alenycouto hivinfectionineasternandsouthernafricahighestburdenlargestchallengesgreatestpotential
AT paulavaz hivinfectionineasternandsouthernafricahighestburdenlargestchallengesgreatestpotential
AT marcovitoria hivinfectionineasternandsouthernafricahighestburdenlargestchallengesgreatestpotential
AT lucasmolfino hivinfectionineasternandsouthernafricahighestburdenlargestchallengesgreatestpotential
AT racheltidowu hivinfectionineasternandsouthernafricahighestburdenlargestchallengesgreatestpotential
AT nileshbhatt hivinfectionineasternandsouthernafricahighestburdenlargestchallengesgreatestpotential
AT denisenaniche hivinfectionineasternandsouthernafricahighestburdenlargestchallengesgreatestpotential
AT peternlesouef hivinfectionineasternandsouthernafricahighestburdenlargestchallengesgreatestpotential