Development and optimization of proniosomal gel containing etodolac: in-vitro, ex-vivo and in-vivo evaluation
Abstract Introduction: Etodolac is used in the treatment of acute pain and inflammation. It has low solubility because of high hydrophobicity and it is reported that upon oral administration shows gastric disturbances. This encourages the development of topical vesicular formulation. Method: In...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
Facultad de Farmacia, Universidad de Granada
2021-09-01
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Series: | Ars Pharmaceutica |
Subjects: | |
Online Access: | http://scielo.isciii.es/scielo.php?script=sci_arttext&pid=S2340-98942021000300290&tlng=en |