Clinical Experience of Intra-Arterial Therapy in Patients with Acute Ischemic Stroke from a Single Institute
Purpose To compare the efficacy and safety between intra-arterial therapy (IAT) and intra-venous and intra-arterial combined therapy (IVIACT) in patients with acute ischemic stroke in the anterior circulation territory. Materials and Methods Forty-one patients treated with IAT using Solitaire w...
| Main Authors: | , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
The Korean Society of Radiology
2016-11-01
|
| Series: | 대한영상의학회지 |
| Subjects: | |
| Online Access: | https://doi.org/10.3348/jksr.2016.75.5.346 |
| _version_ | 1818512830764154880 |
|---|---|
| author | So Young Park Hanbin Lee Jonguk Kim Seung Hun Oh Jinkwon Kim Nam Keun Kim Sang Heum Kim Ok Joon Kim |
| author_facet | So Young Park Hanbin Lee Jonguk Kim Seung Hun Oh Jinkwon Kim Nam Keun Kim Sang Heum Kim Ok Joon Kim |
| author_sort | So Young Park |
| collection | DOAJ |
| description | Purpose
To compare the efficacy and safety between intra-arterial therapy (IAT) and intra-venous and intra-arterial combined therapy (IVIACT) in patients with acute ischemic stroke in the anterior circulation territory.
Materials and Methods
Forty-one patients treated with IAT using Solitaire were retrospectively reviewed. Nineteen patients were treated with IAT, twenty-two patients were treated with IVIACT, and ten patients of the forty-one patients were managed with multimodal treatment like stent, balloon angioplasty etc. We investigated the rate of recanalization and hemorrhage, NIH stroke scale and 3-month modified Rankin Scale.
Results
The overall recanalization rate was 93% and symptomatic ICH occurred in 10% of the patients. There was no difference in hemorrhage, recanalization rate, and early improvement between IAT and IVIACT. Good outcome was more frequently observed in 59% of the patients with IVIACT than 36% of the patients treated with IAT without any significant difference. The patients managed with multimodal treatment did not show any significant hemorrhage outcome.
Conclusion
IAT using Solitaire is a useful treatment method without high risk in patients with acute ischemic stroke in the anterior circulation territory. Also, IVIACT and multimodal treatment might be considered as reasonable therapeutic options in these patients. |
| first_indexed | 2024-12-10T23:52:33Z |
| format | Article |
| id | doaj.art-c8a6a915f12746c5a77de48830e486e9 |
| institution | Directory Open Access Journal |
| issn | 1738-2637 2288-2928 |
| language | English |
| last_indexed | 2024-12-10T23:52:33Z |
| publishDate | 2016-11-01 |
| publisher | The Korean Society of Radiology |
| record_format | Article |
| series | 대한영상의학회지 |
| spelling | doaj.art-c8a6a915f12746c5a77de48830e486e92022-12-22T01:28:43ZengThe Korean Society of Radiology대한영상의학회지1738-26372288-29282016-11-01755346353https://doi.org/10.3348/jksr.2016.75.5.346Clinical Experience of Intra-Arterial Therapy in Patients with Acute Ischemic Stroke from a Single InstituteSo Young Park0Hanbin Lee1Jonguk Kim2Seung Hun Oh3Jinkwon Kim4Nam Keun Kim5Sang Heum Kim6Ok Joon Kim7Department of Neurology, Seoul National University-Seoul Metropolitan Government Boramae Medical Center, Seoul, KoreaDepartment of Neurology, CHA Bundang Medical Center, CHA University, Seongnam, KoreaDepartment of Neurology, CHA Bundang Medical Center, CHA University, Seongnam, KoreaDepartment of Neurology, CHA Bundang Medical Center, CHA University, Seongnam, KoreaDepartment of Neurology, CHA Bundang Medical Center, CHA University, Seongnam, KoreaInstitute for Clinical Research, School of Medicine, CHA University, Seongnam, KoreaDepartment of Radiology, CHA Bundang Medical Center, CHA University, Seongnam, KoreaDepartment of Neurology, CHA Bundang Medical Center, CHA University, Seongnam, KoreaPurpose To compare the efficacy and safety between intra-arterial therapy (IAT) and intra-venous and intra-arterial combined therapy (IVIACT) in patients with acute ischemic stroke in the anterior circulation territory. Materials and Methods Forty-one patients treated with IAT using Solitaire were retrospectively reviewed. Nineteen patients were treated with IAT, twenty-two patients were treated with IVIACT, and ten patients of the forty-one patients were managed with multimodal treatment like stent, balloon angioplasty etc. We investigated the rate of recanalization and hemorrhage, NIH stroke scale and 3-month modified Rankin Scale. Results The overall recanalization rate was 93% and symptomatic ICH occurred in 10% of the patients. There was no difference in hemorrhage, recanalization rate, and early improvement between IAT and IVIACT. Good outcome was more frequently observed in 59% of the patients with IVIACT than 36% of the patients treated with IAT without any significant difference. The patients managed with multimodal treatment did not show any significant hemorrhage outcome. Conclusion IAT using Solitaire is a useful treatment method without high risk in patients with acute ischemic stroke in the anterior circulation territory. Also, IVIACT and multimodal treatment might be considered as reasonable therapeutic options in these patients.https://doi.org/10.3348/jksr.2016.75.5.346strokemechanical thrombolysistissue plasminogen activator |
| spellingShingle | So Young Park Hanbin Lee Jonguk Kim Seung Hun Oh Jinkwon Kim Nam Keun Kim Sang Heum Kim Ok Joon Kim Clinical Experience of Intra-Arterial Therapy in Patients with Acute Ischemic Stroke from a Single Institute 대한영상의학회지 stroke mechanical thrombolysis tissue plasminogen activator |
| title | Clinical Experience of Intra-Arterial Therapy in Patients with Acute Ischemic Stroke from a Single Institute |
| title_full | Clinical Experience of Intra-Arterial Therapy in Patients with Acute Ischemic Stroke from a Single Institute |
| title_fullStr | Clinical Experience of Intra-Arterial Therapy in Patients with Acute Ischemic Stroke from a Single Institute |
| title_full_unstemmed | Clinical Experience of Intra-Arterial Therapy in Patients with Acute Ischemic Stroke from a Single Institute |
| title_short | Clinical Experience of Intra-Arterial Therapy in Patients with Acute Ischemic Stroke from a Single Institute |
| title_sort | clinical experience of intra arterial therapy in patients with acute ischemic stroke from a single institute |
| topic | stroke mechanical thrombolysis tissue plasminogen activator |
| url | https://doi.org/10.3348/jksr.2016.75.5.346 |
| work_keys_str_mv | AT soyoungpark clinicalexperienceofintraarterialtherapyinpatientswithacuteischemicstrokefromasingleinstitute AT hanbinlee clinicalexperienceofintraarterialtherapyinpatientswithacuteischemicstrokefromasingleinstitute AT jongukkim clinicalexperienceofintraarterialtherapyinpatientswithacuteischemicstrokefromasingleinstitute AT seunghunoh clinicalexperienceofintraarterialtherapyinpatientswithacuteischemicstrokefromasingleinstitute AT jinkwonkim clinicalexperienceofintraarterialtherapyinpatientswithacuteischemicstrokefromasingleinstitute AT namkeunkim clinicalexperienceofintraarterialtherapyinpatientswithacuteischemicstrokefromasingleinstitute AT sangheumkim clinicalexperienceofintraarterialtherapyinpatientswithacuteischemicstrokefromasingleinstitute AT okjoonkim clinicalexperienceofintraarterialtherapyinpatientswithacuteischemicstrokefromasingleinstitute |