DIAGNOSIS OF ALCOHOL INTOXICATION IN VICTIMS OF EMERGENCIES

Relevance. In the case of death from injury, the question of whether the victim was intoxicated and to what extent, as the presence of alcohol intoxication could have affected the thanatogenesis of death is important. A reliable method of determining the concentration of ethanol in the body is its s...

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Main Authors: О.P. Babkina, D.О. Matyukhin, I.А. Ushko
Format: Article
Language:English
Published: Bogomolets National Medical University 2020-06-01
Series:Медична наука України
Subjects:
Online Access:https://msu-journal.com/index.php/journal/article/view/216
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author О.P. Babkina
D.О. Matyukhin
I.А. Ushko
author_facet О.P. Babkina
D.О. Matyukhin
I.А. Ushko
author_sort О.P. Babkina
collection DOAJ
description Relevance. In the case of death from injury, the question of whether the victim was intoxicated and to what extent, as the presence of alcohol intoxication could have affected the thanatogenesis of death is important. A reliable method of determining the concentration of ethanol in the body is its study in the blood, urine, and cerebrospinal fluid. But in extreme conditions, in large-scale disasters, during military conflicts, there may be difficulties in the selection, storage, transportation, and research of biological fluids. Therefore, the search for reliable non-invasive rapid methods is relevant. The objective is the development of a set of criteria for improving the accuracy of detecting the presence of ethanol and determining its amount in deaths due to trauma in emergencies by non-invasive rapid methods. Materials and methods. Review of scientific publications in international electronic scientometric databases PubMed, Embase, and Scopus by keywords. Search depth - 10 years (2008-2018). Comparison of literature data with the results of own research on the possibility of diagnosing alcohol intoxication to detect the presence and determination of ethanol in biological fluids (saliva, blood, urine) of persons who died and died in emergencies by indicative and evidentiary methods. Results. The possibility of using the non-invasive express method (indicator test strips) as a guide to detecting the presence and quantification of ethanol in the saliva of deaths and deaths from injuries in emergencies, conflicts, in the absence of the necessary conditions for blood storage and urine (lack of power supply, the impossibility of freezing objects, storage, destruction of objects during transportation, etc.) was described. It is proved that the average result of the quantitative content of ethanol in blood and urine, found in the evidence-based method of research (gas-liquid chromatography), coincides and confirms the result obtained by us in conducting a non-invasive rapid method using indicator test strips. In the course of the conducted researches, the conformity concerning objectivity and correctness of detection of the presence and quantitative content of ethyl alcohol with the use of indicator test strips which is confirmed by researches of blood, urine by evidential methods (gas-liquid chromatography) is proved. Conclusion. A non-invasive rapid method (indicator test strips) can be used as a guide to detect the presence of ethyl alcohol and determine its quantitative content in the saliva of the dead and deceased, with subsequent confirmation by evidence-based methods of research (gas-liquid chromatography) of blood, urine.
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spelling doaj.art-c8aaa71e198e42b697d6f67a5995f0ed2022-12-21T23:30:28ZengBogomolets National Medical UniversityМедична наука України2664-472X2664-47382020-06-01162454910.32345/2664-4738.2.2020.8216DIAGNOSIS OF ALCOHOL INTOXICATION IN VICTIMS OF EMERGENCIESО.P. Babkina0D.О. Matyukhin1I.А. Ushko2O.O. Bogomolets national medical university, Kyiv, UkraineLuhansk State Medical University, Rubizhne, UkraineO.O. Bogomolets national medical university, Kyiv, UkraineRelevance. In the case of death from injury, the question of whether the victim was intoxicated and to what extent, as the presence of alcohol intoxication could have affected the thanatogenesis of death is important. A reliable method of determining the concentration of ethanol in the body is its study in the blood, urine, and cerebrospinal fluid. But in extreme conditions, in large-scale disasters, during military conflicts, there may be difficulties in the selection, storage, transportation, and research of biological fluids. Therefore, the search for reliable non-invasive rapid methods is relevant. The objective is the development of a set of criteria for improving the accuracy of detecting the presence of ethanol and determining its amount in deaths due to trauma in emergencies by non-invasive rapid methods. Materials and methods. Review of scientific publications in international electronic scientometric databases PubMed, Embase, and Scopus by keywords. Search depth - 10 years (2008-2018). Comparison of literature data with the results of own research on the possibility of diagnosing alcohol intoxication to detect the presence and determination of ethanol in biological fluids (saliva, blood, urine) of persons who died and died in emergencies by indicative and evidentiary methods. Results. The possibility of using the non-invasive express method (indicator test strips) as a guide to detecting the presence and quantification of ethanol in the saliva of deaths and deaths from injuries in emergencies, conflicts, in the absence of the necessary conditions for blood storage and urine (lack of power supply, the impossibility of freezing objects, storage, destruction of objects during transportation, etc.) was described. It is proved that the average result of the quantitative content of ethanol in blood and urine, found in the evidence-based method of research (gas-liquid chromatography), coincides and confirms the result obtained by us in conducting a non-invasive rapid method using indicator test strips. In the course of the conducted researches, the conformity concerning objectivity and correctness of detection of the presence and quantitative content of ethyl alcohol with the use of indicator test strips which is confirmed by researches of blood, urine by evidential methods (gas-liquid chromatography) is proved. Conclusion. A non-invasive rapid method (indicator test strips) can be used as a guide to detect the presence of ethyl alcohol and determine its quantitative content in the saliva of the dead and deceased, with subsequent confirmation by evidence-based methods of research (gas-liquid chromatography) of blood, urine.https://msu-journal.com/index.php/journal/article/view/216diagnosis, alcohol intoxication, ethyl alcohol, test strips, gas-liquid chromatography, dynamics, trauma, mortality
spellingShingle О.P. Babkina
D.О. Matyukhin
I.А. Ushko
DIAGNOSIS OF ALCOHOL INTOXICATION IN VICTIMS OF EMERGENCIES
Медична наука України
diagnosis, alcohol intoxication, ethyl alcohol, test strips, gas-liquid chromatography, dynamics, trauma, mortality
title DIAGNOSIS OF ALCOHOL INTOXICATION IN VICTIMS OF EMERGENCIES
title_full DIAGNOSIS OF ALCOHOL INTOXICATION IN VICTIMS OF EMERGENCIES
title_fullStr DIAGNOSIS OF ALCOHOL INTOXICATION IN VICTIMS OF EMERGENCIES
title_full_unstemmed DIAGNOSIS OF ALCOHOL INTOXICATION IN VICTIMS OF EMERGENCIES
title_short DIAGNOSIS OF ALCOHOL INTOXICATION IN VICTIMS OF EMERGENCIES
title_sort diagnosis of alcohol intoxication in victims of emergencies
topic diagnosis, alcohol intoxication, ethyl alcohol, test strips, gas-liquid chromatography, dynamics, trauma, mortality
url https://msu-journal.com/index.php/journal/article/view/216
work_keys_str_mv AT opbabkina diagnosisofalcoholintoxicationinvictimsofemergencies
AT domatyukhin diagnosisofalcoholintoxicationinvictimsofemergencies
AT iaushko diagnosisofalcoholintoxicationinvictimsofemergencies