Carbon-nanoparticle-triggered acute lung inflammation and its resolution are not altered in PPARγ-defective (P465L) mice

Carbon-nanoparticle-triggered acute lung inflammation and its resolution are not altered in PPARγ-defective (P465L) mice

<p>Abstract</p> <p>Background</p> <p>The alveolar macrophage (AM) - first line of innate immune defence against pathogens and environmental irritants - constitutively expresses peroxisome-proliferator activated receptor γ (PPARγ). PPARγ ligand-induced activation keeps t...

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Bibliographic Details
Main Authors: Stoeger Tobias, de Angelis Martin, Rödel Heiko G, Vidal-Puig Antonio, Götz Alexander A
Format: Article
Language:English
Published: BMC 2011-09-01
Series:Particle and Fibre Toxicology
Subjects:
peroxisome-proliverator activated receptor γ
carbon-nano particle
pulmonary inflammation
chronic lung disease
challenge
immune cell
broncho-alveolar lavage (BAL)
inflammatory marker
Online Access:http://www.particleandfibretoxicology.com/content/8/1/28

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