Mapping the Plasticity of Morphology, Molecular Properties and Function in Mouse Primary Microglia

Mapping the Plasticity of Morphology, Molecular Properties and Function in Mouse Primary Microglia

Microglia exert diverse functions by responding in diverse ways to different stimuli, yet little is known about the plasticity of various phenotypes that microglia display. We used interferon (IFN)-γ, interleukin (IL)-4 and IL-10 to induce different phenotypes in mouse primary microglia. RNA sequenc...

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Bibliographic Details
Main Authors: Xue Jiang, Hui He, Li Mo, Qin Liu, Fan Yang, Ying Zhou, Liangyuan Li, Dapeng Su, Saini Yi, Jinqiang Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-01-01
Series:Frontiers in Cellular Neuroscience
Subjects:
microglia
phenotypes
morphology
phagocytosis
neurotoxicity
plasticity
Online Access:https://www.frontiersin.org/articles/10.3389/fncel.2021.811061/full

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