Histopathologic Differentiation between Enchondroma and Well-differentiated Chondrosarcoma: Evaluating the Efficacy of Diagnostic Histologic Structures
Background and aims. Well-differentiated chondrosarcoma and enchondroma are similar in histopathologic aspects; therefore, special methods should be used to make a distinction between these benign and malignant tumors. The aim of this study was to evaluate the efficacy of a histopathologic method...
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| Format: | Article |
| Language: | English |
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Tabriz University of Medical Sciences
2011-09-01
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| Series: | Journal of Dental Research, Dental Clinics, Dental Prospects |
| Subjects: | |
| Online Access: | http://dentistry.tbzmed.ac.ir/joddd/index.php/joddd/article/view/297/206 |
| _version_ | 1818083286568665088 |
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| author | Shams Shariat Torbaghan Mahdi Ashouri Noushin Jalayer Naderi Nima Baherini |
| author_facet | Shams Shariat Torbaghan Mahdi Ashouri Noushin Jalayer Naderi Nima Baherini |
| author_sort | Shams Shariat Torbaghan |
| collection | DOAJ |
| description | Background and aims. Well-differentiated chondrosarcoma and enchondroma are similar in histopathologic aspects;
therefore, special methods should be used to make a distinction between these benign and malignant tumors. The aim of this
study was to evaluate the efficacy of a histopathologic method in the long-term follow-up for differentiating these lesions.
Materials and methods. The medical records of patients with histopathologic diagnosis of chondrosarcoma and enchondroma
were retrieved from the Institute of Cancer, Department of Pathology from 1981 to 2007 in this retrospective
study. A total of 14 patients with chondrosarcoma and 7 patients with enchondroma were included. Tumor lobulation pattern
and fibrous tissue around the lesions were used for histopathologic differentiation between well-differentiated chondrosarcoma
and enchondroma. Method accuracy was evaluated by tumor recurrence in the long-term follow-up.
Results. In the well-differentiated chondrosarcoma group, the follow-up period was 97 months. All the patients (100%)
experienced recurrence. In the enchondroma group, the follow-up period was 129 months. There was no recurrence in this
group.
Conclusion. Lobulation pattern and fibrous tissue formation around the tumor can be an effective and helpful indicator
for histopathologic differentiation between enchondroma and well-differentiated chondrosarcoma. |
| first_indexed | 2024-12-10T19:35:35Z |
| format | Article |
| id | doaj.art-c8b456aa51d3423fb96c0b60d1caef89 |
| institution | Directory Open Access Journal |
| issn | 2008-210X 2008-2118 |
| language | English |
| last_indexed | 2024-12-10T19:35:35Z |
| publishDate | 2011-09-01 |
| publisher | Tabriz University of Medical Sciences |
| record_format | Article |
| series | Journal of Dental Research, Dental Clinics, Dental Prospects |
| spelling | doaj.art-c8b456aa51d3423fb96c0b60d1caef892022-12-22T01:36:08ZengTabriz University of Medical SciencesJournal of Dental Research, Dental Clinics, Dental Prospects2008-210X2008-21182011-09-015398101Histopathologic Differentiation between Enchondroma and Well-differentiated Chondrosarcoma: Evaluating the Efficacy of Diagnostic Histologic StructuresShams Shariat Torbaghan0Mahdi Ashouri1Noushin Jalayer Naderi2Nima Baherini 3Professor, Department of Pathology, Institute of Cancer, Faculty of Dentistry, Shahed University, Tehran, Iran Oral and Maxillofacial Pathologist, Private Practice, Tehran, IranAssistant Professor, Department of Oral and Maxillofacial Pathology, Faculty of Dentistry, Shahed University, Tehran, Iran Dentist, Private Practice, Tehran, IranBackground and aims. Well-differentiated chondrosarcoma and enchondroma are similar in histopathologic aspects; therefore, special methods should be used to make a distinction between these benign and malignant tumors. The aim of this study was to evaluate the efficacy of a histopathologic method in the long-term follow-up for differentiating these lesions. Materials and methods. The medical records of patients with histopathologic diagnosis of chondrosarcoma and enchondroma were retrieved from the Institute of Cancer, Department of Pathology from 1981 to 2007 in this retrospective study. A total of 14 patients with chondrosarcoma and 7 patients with enchondroma were included. Tumor lobulation pattern and fibrous tissue around the lesions were used for histopathologic differentiation between well-differentiated chondrosarcoma and enchondroma. Method accuracy was evaluated by tumor recurrence in the long-term follow-up. Results. In the well-differentiated chondrosarcoma group, the follow-up period was 97 months. All the patients (100%) experienced recurrence. In the enchondroma group, the follow-up period was 129 months. There was no recurrence in this group. Conclusion. Lobulation pattern and fibrous tissue formation around the tumor can be an effective and helpful indicator for histopathologic differentiation between enchondroma and well-differentiated chondrosarcoma.http://dentistry.tbzmed.ac.ir/joddd/index.php/joddd/article/view/297/206EnchondromaChondrosarcomaHistopathologic differentiationClinical follow-up |
| spellingShingle | Shams Shariat Torbaghan Mahdi Ashouri Noushin Jalayer Naderi Nima Baherini Histopathologic Differentiation between Enchondroma and Well-differentiated Chondrosarcoma: Evaluating the Efficacy of Diagnostic Histologic Structures Journal of Dental Research, Dental Clinics, Dental Prospects Enchondroma Chondrosarcoma Histopathologic differentiation Clinical follow-up |
| title | Histopathologic Differentiation between Enchondroma and Well-differentiated Chondrosarcoma: Evaluating the Efficacy of Diagnostic Histologic Structures |
| title_full | Histopathologic Differentiation between Enchondroma and Well-differentiated Chondrosarcoma: Evaluating the Efficacy of Diagnostic Histologic Structures |
| title_fullStr | Histopathologic Differentiation between Enchondroma and Well-differentiated Chondrosarcoma: Evaluating the Efficacy of Diagnostic Histologic Structures |
| title_full_unstemmed | Histopathologic Differentiation between Enchondroma and Well-differentiated Chondrosarcoma: Evaluating the Efficacy of Diagnostic Histologic Structures |
| title_short | Histopathologic Differentiation between Enchondroma and Well-differentiated Chondrosarcoma: Evaluating the Efficacy of Diagnostic Histologic Structures |
| title_sort | histopathologic differentiation between enchondroma and well differentiated chondrosarcoma evaluating the efficacy of diagnostic histologic structures |
| topic | Enchondroma Chondrosarcoma Histopathologic differentiation Clinical follow-up |
| url | http://dentistry.tbzmed.ac.ir/joddd/index.php/joddd/article/view/297/206 |
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