Advantage in privacy protection by using synchronous video observed treatment enhances treatment adherence among patients with latent tuberculosis infection
Background: Treatment of latent tuberculosis infection (LTBI) is an important strategy for active disease prevention. Conventional in-person DOT (CDOT) programs are challenged by patient dissatisfaction over problems of convenience and privacy. The present study assessed satisfaction to DOT program...
| Main Authors: | , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2020-09-01
|
| Series: | Journal of Infection and Public Health |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1876034120304147 |
| _version_ | 1818136798381998080 |
|---|---|
| author | Szu-Hsuan Chen Irene Wang Han-Lin Hsu Chi-Ching Huang Yi-Jun Liu Denise Utami Putri Chih-Hsin Lee |
| author_facet | Szu-Hsuan Chen Irene Wang Han-Lin Hsu Chi-Ching Huang Yi-Jun Liu Denise Utami Putri Chih-Hsin Lee |
| author_sort | Szu-Hsuan Chen |
| collection | DOAJ |
| description | Background: Treatment of latent tuberculosis infection (LTBI) is an important strategy for active disease prevention. Conventional in-person DOT (CDOT) programs are challenged by patient dissatisfaction over problems of convenience and privacy. The present study assessed satisfaction to DOT program and treatment adherence of synchronous video observed treatment (SVOT) programs from patients’ perspectives. Methods: A two-part questionnaire was presented to 240 subjects with LTBI who received a 9-month isoniazid treatment regimen along with mandatory DOT monitoring during January 2014 to December 2017. Results: Satisfactions with location arrangement (p < 0.001), ensuring treatment adherence (p = 0.027), and privacy issues (p = 0.005) were superior in the SVOT group. The overall rate of LTBI treatment completion was 91.25%. One (1.25%) and 20 (12.50%) of the participants in the SVOT and CDOT groups, respectively, quit LTBI treatment (p = 0.008). Development of adverse events [adjusted hazard ratio, aHR 8.01 (3.42–18.79)], and the concern of privacy infringement [aHR 5.86 (2.69–12.76)] by the DOT program independently increase the risk of withdrawal. SVOT program [aHR 0.21 (0.06–0.68)] and a belief in the importance of adherence on treatment efficacy [aHR 0.29 (0.08–0.98)] were independent predictors preventing patients from withdrawing from treatment. Conclusions: A comprehensive patient-centered DOT program enables high treatment adherence for the 9-month isoniazid LTBI treatment. Furthermore, SVOT was associated with superior patients’ satisfactions which translate into higher treatment completion rates. As treatment adherence is the key to the efficacy of LTBI treatment, SVOT should be a reasonable supplement for LTBI treatment. |
| first_indexed | 2024-12-11T09:46:08Z |
| format | Article |
| id | doaj.art-c8b63ab47108405493a746f4d530203a |
| institution | Directory Open Access Journal |
| issn | 1876-0341 |
| language | English |
| last_indexed | 2024-12-11T09:46:08Z |
| publishDate | 2020-09-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Journal of Infection and Public Health |
| spelling | doaj.art-c8b63ab47108405493a746f4d530203a2022-12-22T01:12:33ZengElsevierJournal of Infection and Public Health1876-03412020-09-0113913541359Advantage in privacy protection by using synchronous video observed treatment enhances treatment adherence among patients with latent tuberculosis infectionSzu-Hsuan Chen0Irene Wang1Han-Lin Hsu2Chi-Ching Huang3Yi-Jun Liu4Denise Utami Putri5Chih-Hsin Lee6Department of Health, Taipei City Government, Taipei 11008, TaiwanDivision of Pulmonary Medicine, Department of Internal Medicine, School of Medicine, College of Medicine, Taipei Medical University, Taipei 11031, Taiwan; Pulmonary Research Center, Wan Fang Hospital, Taipei Medical University, Taipei 11696, TaiwanPulmonary Research Center, Wan Fang Hospital, Taipei Medical University, Taipei 11696, Taiwan; School of Respiratory Therapy, College of Medicine, Taipei Medical University, Taipei 11031, TaiwanDepartment of Health, Taipei City Government, Taipei 11008, TaiwanPulmonary Research Center, Wan Fang Hospital, Taipei Medical University, Taipei 11696, TaiwanPulmonary Research Center, Wan Fang Hospital, Taipei Medical University, Taipei 11696, TaiwanDivision of Pulmonary Medicine, Department of Internal Medicine, School of Medicine, College of Medicine, Taipei Medical University, Taipei 11031, Taiwan; Pulmonary Research Center, Wan Fang Hospital, Taipei Medical University, Taipei 11696, Taiwan; Corresponding author at: 250 Wuxing St., Taipei 11031, Taiwan.Background: Treatment of latent tuberculosis infection (LTBI) is an important strategy for active disease prevention. Conventional in-person DOT (CDOT) programs are challenged by patient dissatisfaction over problems of convenience and privacy. The present study assessed satisfaction to DOT program and treatment adherence of synchronous video observed treatment (SVOT) programs from patients’ perspectives. Methods: A two-part questionnaire was presented to 240 subjects with LTBI who received a 9-month isoniazid treatment regimen along with mandatory DOT monitoring during January 2014 to December 2017. Results: Satisfactions with location arrangement (p < 0.001), ensuring treatment adherence (p = 0.027), and privacy issues (p = 0.005) were superior in the SVOT group. The overall rate of LTBI treatment completion was 91.25%. One (1.25%) and 20 (12.50%) of the participants in the SVOT and CDOT groups, respectively, quit LTBI treatment (p = 0.008). Development of adverse events [adjusted hazard ratio, aHR 8.01 (3.42–18.79)], and the concern of privacy infringement [aHR 5.86 (2.69–12.76)] by the DOT program independently increase the risk of withdrawal. SVOT program [aHR 0.21 (0.06–0.68)] and a belief in the importance of adherence on treatment efficacy [aHR 0.29 (0.08–0.98)] were independent predictors preventing patients from withdrawing from treatment. Conclusions: A comprehensive patient-centered DOT program enables high treatment adherence for the 9-month isoniazid LTBI treatment. Furthermore, SVOT was associated with superior patients’ satisfactions which translate into higher treatment completion rates. As treatment adherence is the key to the efficacy of LTBI treatment, SVOT should be a reasonable supplement for LTBI treatment.http://www.sciencedirect.com/science/article/pii/S1876034120304147TuberculosisDirectly observed treatmentTreatment adherenceLatent tuberculosis treatmentStigma |
| spellingShingle | Szu-Hsuan Chen Irene Wang Han-Lin Hsu Chi-Ching Huang Yi-Jun Liu Denise Utami Putri Chih-Hsin Lee Advantage in privacy protection by using synchronous video observed treatment enhances treatment adherence among patients with latent tuberculosis infection Journal of Infection and Public Health Tuberculosis Directly observed treatment Treatment adherence Latent tuberculosis treatment Stigma |
| title | Advantage in privacy protection by using synchronous video observed treatment enhances treatment adherence among patients with latent tuberculosis infection |
| title_full | Advantage in privacy protection by using synchronous video observed treatment enhances treatment adherence among patients with latent tuberculosis infection |
| title_fullStr | Advantage in privacy protection by using synchronous video observed treatment enhances treatment adherence among patients with latent tuberculosis infection |
| title_full_unstemmed | Advantage in privacy protection by using synchronous video observed treatment enhances treatment adherence among patients with latent tuberculosis infection |
| title_short | Advantage in privacy protection by using synchronous video observed treatment enhances treatment adherence among patients with latent tuberculosis infection |
| title_sort | advantage in privacy protection by using synchronous video observed treatment enhances treatment adherence among patients with latent tuberculosis infection |
| topic | Tuberculosis Directly observed treatment Treatment adherence Latent tuberculosis treatment Stigma |
| url | http://www.sciencedirect.com/science/article/pii/S1876034120304147 |
| work_keys_str_mv | AT szuhsuanchen advantageinprivacyprotectionbyusingsynchronousvideoobservedtreatmentenhancestreatmentadherenceamongpatientswithlatenttuberculosisinfection AT irenewang advantageinprivacyprotectionbyusingsynchronousvideoobservedtreatmentenhancestreatmentadherenceamongpatientswithlatenttuberculosisinfection AT hanlinhsu advantageinprivacyprotectionbyusingsynchronousvideoobservedtreatmentenhancestreatmentadherenceamongpatientswithlatenttuberculosisinfection AT chichinghuang advantageinprivacyprotectionbyusingsynchronousvideoobservedtreatmentenhancestreatmentadherenceamongpatientswithlatenttuberculosisinfection AT yijunliu advantageinprivacyprotectionbyusingsynchronousvideoobservedtreatmentenhancestreatmentadherenceamongpatientswithlatenttuberculosisinfection AT deniseutamiputri advantageinprivacyprotectionbyusingsynchronousvideoobservedtreatmentenhancestreatmentadherenceamongpatientswithlatenttuberculosisinfection AT chihhsinlee advantageinprivacyprotectionbyusingsynchronousvideoobservedtreatmentenhancestreatmentadherenceamongpatientswithlatenttuberculosisinfection |