Analysis of Peripapillary Intrachoroidal Cavitation and Myopic Peripapillary Distortions in Polar Regions by Optical Coherence Tomography
Adèle Ehongo,1 Noélie Bacq,1 Nacima Kisma,1 Artemise Dugauquier,1 Yassir Alaoui Mhammedi,1 Kevin Coppens,2 Françoise Bremer,1 Karelle Leroy3 1Ophthalmology Department, Erasmus Hospital, Brussels, 1070, Belgium; 2Statistician, Cosma Consulting, Enghien 7850, Belgium; 3Histology Department, Erasmus Ca...
| Main Authors: | , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Dove Medical Press
2022-08-01
|
| Series: | Clinical Ophthalmology |
| Subjects: | |
| Online Access: | https://www.dovepress.com/analysis-of-peripapillary-intrachoroidal-cavitation-and-myopic-peripap-peer-reviewed-fulltext-article-OPTH |
| _version_ | 1828433959709573120 |
|---|---|
| author | Ehongo A Bacq N Kisma N Dugauquier A Alaoui Mhammedi Y Coppens K Bremer F Leroy K |
| author_facet | Ehongo A Bacq N Kisma N Dugauquier A Alaoui Mhammedi Y Coppens K Bremer F Leroy K |
| author_sort | Ehongo A |
| collection | DOAJ |
| description | Adèle Ehongo,1 Noélie Bacq,1 Nacima Kisma,1 Artemise Dugauquier,1 Yassir Alaoui Mhammedi,1 Kevin Coppens,2 Françoise Bremer,1 Karelle Leroy3 1Ophthalmology Department, Erasmus Hospital, Brussels, 1070, Belgium; 2Statistician, Cosma Consulting, Enghien 7850, Belgium; 3Histology Department, Erasmus Campus, CP 620, Université Libre de Bruxelles, Brussels, 1070, BelgiumCorrespondence: Adèle Ehongo, Ophthalmology Department, Erasmus Hospital, Route de Lennik 808, Brussels, 1070, Belgium, Tel +3225553114, Fax +3225556737, Email adele.ehongo@erasme.ulb.ac.beAbstract: Purpose: To compare the peripapillary polar characteristics in eyes combining peripapillary staphyloma and gamma peripapillary atrophy according to whether peripapillary intrachoroidal cavitation (PICC) was present or absent (combination-group).Patients and methods: This prospective non-interventional cross-sectional study included 667 eyes of 334 subjects. From the polar peripapillary regions to the opening of Bruch’s membrane, the following elements and their topographic relationships were analyzed using optical coherence tomography sections: configuration of the posterior curvature of the choroid, visibility of the subarachnoid space (SAS), and suprachoroidal detachment (SCD). Chi-squared and Fisher exact tests were used for statistical analysis.Results: The protrusion of the posterior choroidal wall, with anterior elevation on either side, observed in both groups progressed and transformed into a wedge-shaped deformity on the side of gamma peripapillary atrophy. This wedge configuration was significantly more frequent in PICC-group than in combination-group (p = 0.004 and p < 0.001) for the upper and lower poles, respectively. SAS was more frequently observed in PICC-group than in combination-group (p = 0.002 and p < 0.001) for the upper and lower poles, respectively. SCD was detected exclusively in PICC-group (p < 0.001, both poles). The wedge-shaped configuration and the SCD were aligned antero-posteriorly with the SAS.Conclusion: We confirmed that PICC is an SCD. We observed its constant alignment with the SAS. We suggest that the tensile forces of the optic nerve sheaths during adduction promote the collapse of the scleral flange onto the SAS, leading to PICC. Further studies are warranted to confirm this hypothesis.Keywords: peripapillary intrachoroidal cavitation, suprachoroidal detachment, gamma peripapillary atrophy, staphyloma, subarachnoid space, myopic complications |
| first_indexed | 2024-12-10T18:43:16Z |
| format | Article |
| id | doaj.art-c8b8c13958bd4a1d953a52a64db20ae8 |
| institution | Directory Open Access Journal |
| issn | 1177-5483 |
| language | English |
| last_indexed | 2024-12-10T18:43:16Z |
| publishDate | 2022-08-01 |
| publisher | Dove Medical Press |
| record_format | Article |
| series | Clinical Ophthalmology |
| spelling | doaj.art-c8b8c13958bd4a1d953a52a64db20ae82022-12-22T01:37:36ZengDove Medical PressClinical Ophthalmology1177-54832022-08-01Volume 162617262977375Analysis of Peripapillary Intrachoroidal Cavitation and Myopic Peripapillary Distortions in Polar Regions by Optical Coherence TomographyEhongo ABacq NKisma NDugauquier AAlaoui Mhammedi YCoppens KBremer FLeroy KAdèle Ehongo,1 Noélie Bacq,1 Nacima Kisma,1 Artemise Dugauquier,1 Yassir Alaoui Mhammedi,1 Kevin Coppens,2 Françoise Bremer,1 Karelle Leroy3 1Ophthalmology Department, Erasmus Hospital, Brussels, 1070, Belgium; 2Statistician, Cosma Consulting, Enghien 7850, Belgium; 3Histology Department, Erasmus Campus, CP 620, Université Libre de Bruxelles, Brussels, 1070, BelgiumCorrespondence: Adèle Ehongo, Ophthalmology Department, Erasmus Hospital, Route de Lennik 808, Brussels, 1070, Belgium, Tel +3225553114, Fax +3225556737, Email adele.ehongo@erasme.ulb.ac.beAbstract: Purpose: To compare the peripapillary polar characteristics in eyes combining peripapillary staphyloma and gamma peripapillary atrophy according to whether peripapillary intrachoroidal cavitation (PICC) was present or absent (combination-group).Patients and methods: This prospective non-interventional cross-sectional study included 667 eyes of 334 subjects. From the polar peripapillary regions to the opening of Bruch’s membrane, the following elements and their topographic relationships were analyzed using optical coherence tomography sections: configuration of the posterior curvature of the choroid, visibility of the subarachnoid space (SAS), and suprachoroidal detachment (SCD). Chi-squared and Fisher exact tests were used for statistical analysis.Results: The protrusion of the posterior choroidal wall, with anterior elevation on either side, observed in both groups progressed and transformed into a wedge-shaped deformity on the side of gamma peripapillary atrophy. This wedge configuration was significantly more frequent in PICC-group than in combination-group (p = 0.004 and p < 0.001) for the upper and lower poles, respectively. SAS was more frequently observed in PICC-group than in combination-group (p = 0.002 and p < 0.001) for the upper and lower poles, respectively. SCD was detected exclusively in PICC-group (p < 0.001, both poles). The wedge-shaped configuration and the SCD were aligned antero-posteriorly with the SAS.Conclusion: We confirmed that PICC is an SCD. We observed its constant alignment with the SAS. We suggest that the tensile forces of the optic nerve sheaths during adduction promote the collapse of the scleral flange onto the SAS, leading to PICC. Further studies are warranted to confirm this hypothesis.Keywords: peripapillary intrachoroidal cavitation, suprachoroidal detachment, gamma peripapillary atrophy, staphyloma, subarachnoid space, myopic complicationshttps://www.dovepress.com/analysis-of-peripapillary-intrachoroidal-cavitation-and-myopic-peripap-peer-reviewed-fulltext-article-OPTHperipapillary intrachoroidal cavitationsuprachoroidal detachmentgamma peripapillary atrophystaphylomasubarachnoid spacemyopic complications. |
| spellingShingle | Ehongo A Bacq N Kisma N Dugauquier A Alaoui Mhammedi Y Coppens K Bremer F Leroy K Analysis of Peripapillary Intrachoroidal Cavitation and Myopic Peripapillary Distortions in Polar Regions by Optical Coherence Tomography Clinical Ophthalmology peripapillary intrachoroidal cavitation suprachoroidal detachment gamma peripapillary atrophy staphyloma subarachnoid space myopic complications. |
| title | Analysis of Peripapillary Intrachoroidal Cavitation and Myopic Peripapillary Distortions in Polar Regions by Optical Coherence Tomography |
| title_full | Analysis of Peripapillary Intrachoroidal Cavitation and Myopic Peripapillary Distortions in Polar Regions by Optical Coherence Tomography |
| title_fullStr | Analysis of Peripapillary Intrachoroidal Cavitation and Myopic Peripapillary Distortions in Polar Regions by Optical Coherence Tomography |
| title_full_unstemmed | Analysis of Peripapillary Intrachoroidal Cavitation and Myopic Peripapillary Distortions in Polar Regions by Optical Coherence Tomography |
| title_short | Analysis of Peripapillary Intrachoroidal Cavitation and Myopic Peripapillary Distortions in Polar Regions by Optical Coherence Tomography |
| title_sort | analysis of peripapillary intrachoroidal cavitation and myopic peripapillary distortions in polar regions by optical coherence tomography |
| topic | peripapillary intrachoroidal cavitation suprachoroidal detachment gamma peripapillary atrophy staphyloma subarachnoid space myopic complications. |
| url | https://www.dovepress.com/analysis-of-peripapillary-intrachoroidal-cavitation-and-myopic-peripap-peer-reviewed-fulltext-article-OPTH |
| work_keys_str_mv | AT ehongoa analysisofperipapillaryintrachoroidalcavitationandmyopicperipapillarydistortionsinpolarregionsbyopticalcoherencetomography AT bacqn analysisofperipapillaryintrachoroidalcavitationandmyopicperipapillarydistortionsinpolarregionsbyopticalcoherencetomography AT kisman analysisofperipapillaryintrachoroidalcavitationandmyopicperipapillarydistortionsinpolarregionsbyopticalcoherencetomography AT dugauquiera analysisofperipapillaryintrachoroidalcavitationandmyopicperipapillarydistortionsinpolarregionsbyopticalcoherencetomography AT alaouimhammediy analysisofperipapillaryintrachoroidalcavitationandmyopicperipapillarydistortionsinpolarregionsbyopticalcoherencetomography AT coppensk analysisofperipapillaryintrachoroidalcavitationandmyopicperipapillarydistortionsinpolarregionsbyopticalcoherencetomography AT bremerf analysisofperipapillaryintrachoroidalcavitationandmyopicperipapillarydistortionsinpolarregionsbyopticalcoherencetomography AT leroyk analysisofperipapillaryintrachoroidalcavitationandmyopicperipapillarydistortionsinpolarregionsbyopticalcoherencetomography |