Research Note: Effect of organic acid mixture on growth performance and Salmonella Typhimurium colonization in broiler chickens
Feed additives can be alternatives to antibiotics for routinely encountered pathogens in the poultry production. The objective of this study was to understand effects of organic acid mixture on growth parameters and Salmonella Typhimurium (ST) colonization in broilers. Organic acid mixture is a feed...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2020-05-01
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| Series: | Poultry Science |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S0032579120300122 |
| _version_ | 1811222152868790272 |
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| author | Pratima Adhikari Sudhir Yadav Douglas E. Cosby Nelson A. Cox Joshua A. Jendza Woo Kyun Kim |
| author_facet | Pratima Adhikari Sudhir Yadav Douglas E. Cosby Nelson A. Cox Joshua A. Jendza Woo Kyun Kim |
| author_sort | Pratima Adhikari |
| collection | DOAJ |
| description | Feed additives can be alternatives to antibiotics for routinely encountered pathogens in the poultry production. The objective of this study was to understand effects of organic acid mixture on growth parameters and Salmonella Typhimurium (ST) colonization in broilers. Organic acid mixture is a feed-grade buffered formic acid and sodium formate mixture (Amasil NA). A total of 800 1-day-old Cobb500 males were fed one of the five dietary treatments: a negative control diet without ST challenge (NC), positive control diet with ST challenge (PC), 0.3% organic acid mixture with ST, 0.6% organic acid mixture with ST, and 0.9% organic acid mixture with ST. Treatments were assigned to 20 pens with 40 chicks/pen and 4 replicates of each treatment. Chickens were challenged with 107 CFU/mL of nalidixic acid–resistant ST (STNAR) 4-D posthatch. In the grower phase, feed conversion rate was significantly reduced in the 9% organic acid mixture compared with the PC. The body weight and body weight gain (BWG) were not affected either in the starter or grower phases. However, in the finisher phase, the nonchallenged NC had higher BWG than the PC (P < 0.05), whereas there were no differences in BWG among the NC and organic acid mixture fed groups. In addition, there was a significant effect of organic acid mixture on the colonization of cecal STNAR. At 9 dpi, cecal STNAR was 3.28 log10 in the PC that was reduced to 2.65 log10 at 0.3%, 1.40 log10 at 0.6%, and 0.84 log10 in 0.9% organic acid mixture. At 24 dpi, cecal STNAR recovery was 0.81, 0.99, 0.53, and 0.33 log10 in the PC and 0.3, 0.6, and 0.9% organic acid mixture, respectively. Similarly, at 38 dpi, cecal STNAR was 0.26, 0.11, 0.33, and 0 log10 in the PC, 0.3, 0.6, and 0.9%, respectively. These results show that organic acid mixture can be one dietary strategy to control ST infection and maintain efficient growth performance. |
| first_indexed | 2024-04-12T08:11:33Z |
| format | Article |
| id | doaj.art-c8baa48138c049088474e47dbd8213f6 |
| institution | Directory Open Access Journal |
| issn | 0032-5791 |
| language | English |
| last_indexed | 2024-04-12T08:11:33Z |
| publishDate | 2020-05-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Poultry Science |
| spelling | doaj.art-c8baa48138c049088474e47dbd8213f62022-12-22T03:40:56ZengElsevierPoultry Science0032-57912020-05-0199526452649Research Note: Effect of organic acid mixture on growth performance and Salmonella Typhimurium colonization in broiler chickensPratima Adhikari0Sudhir Yadav1Douglas E. Cosby2Nelson A. Cox3Joshua A. Jendza4Woo Kyun Kim5Department of Poultry Science, Mississippi State University, Starkville, MS, USADepartment of Poultry Science, University of Georgia, Athens, GA, USAUSDA, ARS, The U.S. National Poultry Research Center, Athens, GA, 30605, USAUSDA, ARS, The U.S. National Poultry Research Center, Athens, GA, 30605, USABASF Corporation, Florham Park, NJ, United StatesDepartment of Poultry Science, University of Georgia, Athens, GA, USA; Corresponding author:Feed additives can be alternatives to antibiotics for routinely encountered pathogens in the poultry production. The objective of this study was to understand effects of organic acid mixture on growth parameters and Salmonella Typhimurium (ST) colonization in broilers. Organic acid mixture is a feed-grade buffered formic acid and sodium formate mixture (Amasil NA). A total of 800 1-day-old Cobb500 males were fed one of the five dietary treatments: a negative control diet without ST challenge (NC), positive control diet with ST challenge (PC), 0.3% organic acid mixture with ST, 0.6% organic acid mixture with ST, and 0.9% organic acid mixture with ST. Treatments were assigned to 20 pens with 40 chicks/pen and 4 replicates of each treatment. Chickens were challenged with 107 CFU/mL of nalidixic acid–resistant ST (STNAR) 4-D posthatch. In the grower phase, feed conversion rate was significantly reduced in the 9% organic acid mixture compared with the PC. The body weight and body weight gain (BWG) were not affected either in the starter or grower phases. However, in the finisher phase, the nonchallenged NC had higher BWG than the PC (P < 0.05), whereas there were no differences in BWG among the NC and organic acid mixture fed groups. In addition, there was a significant effect of organic acid mixture on the colonization of cecal STNAR. At 9 dpi, cecal STNAR was 3.28 log10 in the PC that was reduced to 2.65 log10 at 0.3%, 1.40 log10 at 0.6%, and 0.84 log10 in 0.9% organic acid mixture. At 24 dpi, cecal STNAR recovery was 0.81, 0.99, 0.53, and 0.33 log10 in the PC and 0.3, 0.6, and 0.9% organic acid mixture, respectively. Similarly, at 38 dpi, cecal STNAR was 0.26, 0.11, 0.33, and 0 log10 in the PC, 0.3, 0.6, and 0.9%, respectively. These results show that organic acid mixture can be one dietary strategy to control ST infection and maintain efficient growth performance.http://www.sciencedirect.com/science/article/pii/S0032579120300122organic acidantibiotic alternativebroilers performanceSalmonella Typhimurium |
| spellingShingle | Pratima Adhikari Sudhir Yadav Douglas E. Cosby Nelson A. Cox Joshua A. Jendza Woo Kyun Kim Research Note: Effect of organic acid mixture on growth performance and Salmonella Typhimurium colonization in broiler chickens Poultry Science organic acid antibiotic alternative broilers performance Salmonella Typhimurium |
| title | Research Note: Effect of organic acid mixture on growth performance and Salmonella Typhimurium colonization in broiler chickens |
| title_full | Research Note: Effect of organic acid mixture on growth performance and Salmonella Typhimurium colonization in broiler chickens |
| title_fullStr | Research Note: Effect of organic acid mixture on growth performance and Salmonella Typhimurium colonization in broiler chickens |
| title_full_unstemmed | Research Note: Effect of organic acid mixture on growth performance and Salmonella Typhimurium colonization in broiler chickens |
| title_short | Research Note: Effect of organic acid mixture on growth performance and Salmonella Typhimurium colonization in broiler chickens |
| title_sort | research note effect of organic acid mixture on growth performance and salmonella typhimurium colonization in broiler chickens |
| topic | organic acid antibiotic alternative broilers performance Salmonella Typhimurium |
| url | http://www.sciencedirect.com/science/article/pii/S0032579120300122 |
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