Immunological profile of lactylation-related genes in Crohn’s disease: a comprehensive analysis based on bulk and single-cell RNA sequencing data

Immunological profile of lactylation-related genes in Crohn’s disease: a comprehensive analysis based on bulk and single-cell RNA sequencing data

Abstract Background Crohn's disease (CD) is a disease characterized by intestinal immune dysfunction, often accompanied by metabolic abnormalities. Disturbances in lactate metabolism have been found in the intestine of patients with CD, but studies on the role of lactate and related Lactylation...

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Bibliographic Details
Main Authors: Jingtong Wu, Yinyin Lv, Pei Hao, Ziyi Zhang, Yongtian Zheng, Ermei Chen, Yanyun Fan
Format: Article
Language:English
Published: BMC 2024-03-01
Series:Journal of Translational Medicine
Subjects:
Lactylation
Crohn’s disease
Immune infiltration
Online Access:https://doi.org/10.1186/s12967-024-05092-z

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