Spectrum of Orbito-ocular Tumour in India: Histopathological and Immunohistochemical Study
Introduction: Orbito-ocular tumours are an important cause of morbidity and mortality. Their incidence is low but requires immediate diagnosis and treatment. There are limited research studies on histopathological and immunohistochemical studies of ocular tumour from India and these studies may...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
JCDR Research and Publications Pvt. Ltd.
2022-07-01
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| Series: | National Journal of Laboratory Medicine |
| Subjects: | |
| Online Access: | https://www.njlm.net/articles/PDF/2645/53617_CE[Ra1]_F[SH]_PF1(SG_SHU)_redo_PFA(SHU)_PB(SG_SHU)_PN(SHU).pdf |
| Summary: | Introduction: Orbito-ocular tumours are an important cause
of morbidity and mortality. Their incidence is low but requires
immediate diagnosis and treatment. There are limited research
studies on histopathological and immunohistochemical studies of
ocular tumour from India and these studies may provide valuable
information and aid in accurate diagnosis and management.
Aim: To elucidate distribution of age, sex, location of tumour,
histopathological, immunohistochemical findings and any other
relevant information with respect to orbito-ocular tumours.
Materials and Methods: A retrospective observational analysis
was conducted over a period of five years from March 2008
to February 2013, in the Department of Pathology in a tertiary
care centre, Assam, India. Hospital records of 55 patients with
malignant ocular tumours were collected, reviewed and statistically
analysed.
Results: In the present study, a total of 55 cases were included.
Out of which, two cases were inconclusive due to inadequate
material. Remaining, 53 cases included both intraocular and
orbital malignant tumours. Tumours were found slightly more in
males (34 cases) compared to females (19) with a ratio of 1.8
to 1. Squamous Cell Carcinoma (SCC) comprised the maximum
number (16 cases) followed by Retinoblastoma (RB) in 15 cases
and melanoma in 11 cases. In children most common malignancy
was RB followed by rhadomyosarcoma (RMS).
Conclusion: In this study it was found that SCC was the most
common malignant tumour in adults whereas RB was the most
common tumour in children. |
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| ISSN: | 2277-8551 2455-6882 |