ERCC1 and MGMT Methylation as a Predictive Marker of Relapse and FOLFOX Response in Colorectal Cancer Patients from South Tunisia

Genetic and epigenetic modifications present a major cause of relapse and treatment failure in colorectal cancer. This study aims to appreciate the prognostic and predictive value of ERRC1 and MGMT methylation. We also studied the prognostic impact of the ERCC1 rs11615 polymorphism as well as its ex...

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Bibliographic Details
Main Authors: Dhouha Jamai, Raja Gargouri, Boulbaba Selmi, Abdelmajid Khabir
Format: Article
Language:English
Published: MDPI AG 2023-07-01
Series:Genes
Subjects:
Online Access:https://www.mdpi.com/2073-4425/14/7/1467