N-(4-Methoxyphenyl)-N′-(5-nitro-1,3-thiazol-2-yl)urea

N-(4-Methoxyphenyl)-N′-(5-nitro-1,3-thiazol-2-yl)urea

The title compound, C11H10N4O4S, is a derivative of N-(4-methoxybenzyl)-N′-(5-nitro-1,3-thiazol-2-yl)urea (AR-A014418), a known glycogen synthase kinase 3β (GSK-3β) inhibitor. All non-H atoms in the molecule are essentially coplanar, with an r.m.s. deviation o...

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Bibliographic Details
Main Authors: Alan J. Lough, Justin W. Hicks, John F. Valliant, Alan A. Wilson, Neil Vasdev
Format: Article
Language:English
Published: International Union of Crystallography 2010-09-01
Series:Acta Crystallographica Section E
Online Access:http://scripts.iucr.org/cgi-bin/paper?S1600536810032186
Description
Summary:The title compound, C11H10N4O4S, is a derivative of N-(4-methoxybenzyl)-N′-(5-nitro-1,3-thiazol-2-yl)urea (AR-A014418), a known glycogen synthase kinase 3β (GSK-3β) inhibitor. All non-H atoms in the molecule are essentially coplanar, with an r.m.s. deviation of 0.045 Å and a maximum deviation of 0.115 (2) Å for the carbonyl O atom. In the crystal structure, molecules are linked via N—H...O hydrogen bonds into one-dimensional chains along [101].
ISSN:1600-5368

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