N-(4-Methoxyphenyl)-N′-(5-nitro-1,3-thiazol-2-yl)urea
The title compound, C11H10N4O4S, is a derivative of N-(4-methoxybenzyl)-N′-(5-nitro-1,3-thiazol-2-yl)urea (AR-A014418), a known glycogen synthase kinase 3β (GSK-3β) inhibitor. All non-H atoms in the molecule are essentially coplanar, with an r.m.s. deviation o...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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International Union of Crystallography
2010-09-01
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| Series: | Acta Crystallographica Section E |
| Online Access: | http://scripts.iucr.org/cgi-bin/paper?S1600536810032186 |
| _version_ | 1819106174512922624 |
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| author | Alan J. Lough Justin W. Hicks John F. Valliant Alan A. Wilson Neil Vasdev |
| author_facet | Alan J. Lough Justin W. Hicks John F. Valliant Alan A. Wilson Neil Vasdev |
| author_sort | Alan J. Lough |
| collection | DOAJ |
| description | The title compound, C11H10N4O4S, is a derivative of N-(4-methoxybenzyl)-N′-(5-nitro-1,3-thiazol-2-yl)urea (AR-A014418), a known glycogen synthase kinase 3β (GSK-3β) inhibitor. All non-H atoms in the molecule are essentially coplanar, with an r.m.s. deviation of 0.045 Å and a maximum deviation of 0.115 (2) Å for the carbonyl O atom. In the crystal structure, molecules are linked via N—H...O hydrogen bonds into one-dimensional chains along [101]. |
| first_indexed | 2024-12-22T02:33:57Z |
| format | Article |
| id | doaj.art-c8c8bc2e699e414dbb167ccc6c5b571f |
| institution | Directory Open Access Journal |
| issn | 1600-5368 |
| language | English |
| last_indexed | 2024-12-22T02:33:57Z |
| publishDate | 2010-09-01 |
| publisher | International Union of Crystallography |
| record_format | Article |
| series | Acta Crystallographica Section E |
| spelling | doaj.art-c8c8bc2e699e414dbb167ccc6c5b571f2022-12-21T18:41:49ZengInternational Union of CrystallographyActa Crystallographica Section E1600-53682010-09-01669o2339o233910.1107/S1600536810032186N-(4-Methoxyphenyl)-N′-(5-nitro-1,3-thiazol-2-yl)ureaAlan J. LoughJustin W. HicksJohn F. ValliantAlan A. WilsonNeil VasdevThe title compound, C11H10N4O4S, is a derivative of N-(4-methoxybenzyl)-N′-(5-nitro-1,3-thiazol-2-yl)urea (AR-A014418), a known glycogen synthase kinase 3β (GSK-3β) inhibitor. All non-H atoms in the molecule are essentially coplanar, with an r.m.s. deviation of 0.045 Å and a maximum deviation of 0.115 (2) Å for the carbonyl O atom. In the crystal structure, molecules are linked via N—H...O hydrogen bonds into one-dimensional chains along [101].http://scripts.iucr.org/cgi-bin/paper?S1600536810032186 |
| spellingShingle | Alan J. Lough Justin W. Hicks John F. Valliant Alan A. Wilson Neil Vasdev N-(4-Methoxyphenyl)-N′-(5-nitro-1,3-thiazol-2-yl)urea Acta Crystallographica Section E |
| title | N-(4-Methoxyphenyl)-N′-(5-nitro-1,3-thiazol-2-yl)urea |
| title_full | N-(4-Methoxyphenyl)-N′-(5-nitro-1,3-thiazol-2-yl)urea |
| title_fullStr | N-(4-Methoxyphenyl)-N′-(5-nitro-1,3-thiazol-2-yl)urea |
| title_full_unstemmed | N-(4-Methoxyphenyl)-N′-(5-nitro-1,3-thiazol-2-yl)urea |
| title_short | N-(4-Methoxyphenyl)-N′-(5-nitro-1,3-thiazol-2-yl)urea |
| title_sort | n 4 methoxyphenyl n amp 8242 5 nitro 1 3 thiazol 2 yl urea |
| url | http://scripts.iucr.org/cgi-bin/paper?S1600536810032186 |
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