TLR4 response mediates ethanol-induced neurodevelopment alterations in a model of fetal alcohol spectrum disorders

TLR4 response mediates ethanol-induced neurodevelopment alterations in a model of fetal alcohol spectrum disorders

Abstract Background Inflammation during brain development participates in the pathogenesis of early brain injury and cognitive dysfunctions. Prenatal ethanol exposure affects the developing brain and causes neural impairment, cognitive and behavioral effects, collectively known as fetal alcohol spec...

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Bibliographic Details
Main Authors: María Pascual, Jorge Montesinos, Sandra Montagud-Romero, Jerónimo Forteza, Marta Rodríguez-Arias, José Miñarro, Consuelo Guerri
Format: Article
Language:English
Published: BMC 2017-07-01
Series:Journal of Neuroinflammation
Subjects:
Fetal alcohol spectrum disorders
TLR4
Neuroinflammation
Prenatal ethanol exposure
Cerebral cortex
Serum
Online Access:http://link.springer.com/article/10.1186/s12974-017-0918-2

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