Exploring molecular mechanisms of intra-articular changes in osteonecrosis of femoral head using DIA proteomics and bioinformatics

Exploring molecular mechanisms of intra-articular changes in osteonecrosis of femoral head using DIA proteomics and bioinformatics

Abstract Purpose This study is aimed to delve into the crucial proteins associated with hormonal osteonecrosis of the femoral head (ONFH) and its intra-articular lesions through data-independent acquisition (DIA) proteomics and bioinformatics analysis. Methods We randomly selected samples from eligi...

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Bibliographic Details
Main Authors: Gang Zhao, Yujie Liu, Yongjun Zheng, Mingyang An, Jia Zhang, Jing Zhang, Zhongli Li, Li Chunbao
Format: Article
Language:English
Published: BMC 2024-01-01
Series:Journal of Orthopaedic Surgery and Research
Subjects:
Osteonecrosis of the femoral head
DIA proteomics
Bioinformatics analysis
Differentially expressed proteins
Key regulatory proteins
Online Access:https://doi.org/10.1186/s13018-023-04464-3

Internet

https://doi.org/10.1186/s13018-023-04464-3

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