Interleukin 12 receptor deficiency in a child with recurrent bronchopneumonia and very high IgE levels

Interleukin 12 receptor deficiency in a child with recurrent bronchopneumonia and very high IgE levels

<p>Abstract</p> <p>Interleukin-12 (IL-12) is involved in cellular immune responses against intracellular pathogens by promoting the generation of T naive in T helper 1 (Th1) cells and by increasing interferon-gamma (IFN-gamma) production from T and natural killer (NK) cells. A defe...

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Bibliographic Details
Main Authors: Palamaro Loredana, Giardino Giuliana, Santamaria Francesca, Romano Rosa, Fusco Anna, Montella Silvia, Salerno Mariacarolina, Ursini Matilde, Pignata Claudio
Format: Article
Language:English
Published: BMC 2012-09-01
Series:Italian Journal of Pediatrics
Subjects:
Immunodeficiency
IL-12/IL-12 receptor
Recurrent pneumonia
Online Access:http://www.ijponline.net/content/38/1/46

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