Pulmonary changes among asymptomatic smokers using high-resolution computed tomography and pulmonary function tests
Objective To detect pulmonary changes among asymptomatic smokers using an inspiratory and expiratory high-resolution computed tomography (HRCT) and pulmonary function tests (PFT). Pulmonary changes associated with smoking are now an increasing public health concern. Computed tomography, especially H...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2023-01-01
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| Series: | Egyptian Journal of Chest Disease and Tuberculosis |
| Subjects: | |
| Online Access: | http://www.ejcdt.eg.net/article.asp?issn=0422-7638;year=2023;volume=72;issue=1;spage=112;epage=119;aulast=Ali |
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| author | Ahmed Abd Al-Rahman Ali Mahmoud M Elhabashy Dena M Serag Walaa G.E. Abo Koura Sami S.A. El Dahdouh |
| author_facet | Ahmed Abd Al-Rahman Ali Mahmoud M Elhabashy Dena M Serag Walaa G.E. Abo Koura Sami S.A. El Dahdouh |
| author_sort | Ahmed Abd Al-Rahman Ali |
| collection | DOAJ |
| description | Objective To detect pulmonary changes among asymptomatic smokers using an inspiratory and expiratory high-resolution computed tomography (HRCT) and pulmonary function tests (PFT). Pulmonary changes associated with smoking are now an increasing public health concern. Computed tomography, especially HRCT, is the best choice for visualizing lung morphology. Patients and methods The study was a cohort study conducted at Shebeen Chest Hospital from January 2019 to January 2021. The study was carried out on 120 adult males; 80 of them were asymptomatic smokers and 40 matched healthy nonsmokers served as the control group. All underwent routine chest radiograph, PA view, HRCT (inspiratory, expiratory) film, and PFTs in the form of forced expiratory vital capacity (FVC), forced expiratory volume after 1 s (FEV1), FEV1/FVC, mean forced expiratory flow, and peak expiratory flow. Comparison between the two groups was done according to HRCT and PFT. Result There was significant difference between inspiratory and expiratory HRCT regarding air trapping between cases. Inspiratory air trapping was present in 4% while expiratory air trapping was present in 18%. There was highly significant difference between cases and controls regarding emphysema and bronchial thickening, subpleural line. There was no statistically significant difference between the two groups regarding FVC, forced expiratory flow 25–75, and FEV1/FVC, while there was a significant difference between them regarding PFT pattern results (P<0.05). Conclusion HRCT is the most sensitive imaging modality for diagnosing early emphysema in asymptomatic smokers. HRCT of the lung can detect lung abnormalities noninvasively. |
| first_indexed | 2024-04-10T09:56:59Z |
| format | Article |
| id | doaj.art-c8d18182759641b0b1b6508abb593ff6 |
| institution | Directory Open Access Journal |
| issn | 0422-7638 2090-9950 |
| language | English |
| last_indexed | 2024-04-10T09:56:59Z |
| publishDate | 2023-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Egyptian Journal of Chest Disease and Tuberculosis |
| spelling | doaj.art-c8d18182759641b0b1b6508abb593ff62023-02-16T12:15:27ZengWolters Kluwer Medknow PublicationsEgyptian Journal of Chest Disease and Tuberculosis0422-76382090-99502023-01-0172111211910.4103/ecdt.ecdt_43_22Pulmonary changes among asymptomatic smokers using high-resolution computed tomography and pulmonary function testsAhmed Abd Al-Rahman AliMahmoud M ElhabashyDena M SeragWalaa G.E. Abo KouraSami S.A. El DahdouhObjective To detect pulmonary changes among asymptomatic smokers using an inspiratory and expiratory high-resolution computed tomography (HRCT) and pulmonary function tests (PFT). Pulmonary changes associated with smoking are now an increasing public health concern. Computed tomography, especially HRCT, is the best choice for visualizing lung morphology. Patients and methods The study was a cohort study conducted at Shebeen Chest Hospital from January 2019 to January 2021. The study was carried out on 120 adult males; 80 of them were asymptomatic smokers and 40 matched healthy nonsmokers served as the control group. All underwent routine chest radiograph, PA view, HRCT (inspiratory, expiratory) film, and PFTs in the form of forced expiratory vital capacity (FVC), forced expiratory volume after 1 s (FEV1), FEV1/FVC, mean forced expiratory flow, and peak expiratory flow. Comparison between the two groups was done according to HRCT and PFT. Result There was significant difference between inspiratory and expiratory HRCT regarding air trapping between cases. Inspiratory air trapping was present in 4% while expiratory air trapping was present in 18%. There was highly significant difference between cases and controls regarding emphysema and bronchial thickening, subpleural line. There was no statistically significant difference between the two groups regarding FVC, forced expiratory flow 25–75, and FEV1/FVC, while there was a significant difference between them regarding PFT pattern results (P<0.05). Conclusion HRCT is the most sensitive imaging modality for diagnosing early emphysema in asymptomatic smokers. HRCT of the lung can detect lung abnormalities noninvasively.http://www.ejcdt.eg.net/article.asp?issn=0422-7638;year=2023;volume=72;issue=1;spage=112;epage=119;aulast=Aliasymptomatichigh-resolution computed tomographypulmonary function testpulmonarysmokers |
| spellingShingle | Ahmed Abd Al-Rahman Ali Mahmoud M Elhabashy Dena M Serag Walaa G.E. Abo Koura Sami S.A. El Dahdouh Pulmonary changes among asymptomatic smokers using high-resolution computed tomography and pulmonary function tests Egyptian Journal of Chest Disease and Tuberculosis asymptomatic high-resolution computed tomography pulmonary function test pulmonary smokers |
| title | Pulmonary changes among asymptomatic smokers using high-resolution computed tomography and pulmonary function tests |
| title_full | Pulmonary changes among asymptomatic smokers using high-resolution computed tomography and pulmonary function tests |
| title_fullStr | Pulmonary changes among asymptomatic smokers using high-resolution computed tomography and pulmonary function tests |
| title_full_unstemmed | Pulmonary changes among asymptomatic smokers using high-resolution computed tomography and pulmonary function tests |
| title_short | Pulmonary changes among asymptomatic smokers using high-resolution computed tomography and pulmonary function tests |
| title_sort | pulmonary changes among asymptomatic smokers using high resolution computed tomography and pulmonary function tests |
| topic | asymptomatic high-resolution computed tomography pulmonary function test pulmonary smokers |
| url | http://www.ejcdt.eg.net/article.asp?issn=0422-7638;year=2023;volume=72;issue=1;spage=112;epage=119;aulast=Ali |
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