The association between severe mitral stenosis and the size of the aortic root and the ascending thoracic aorta
Objective: The aim of this study was to examine the role of isolated rheumatic mitral stenosis (MS) in remodeling of the aorta at various locations. Methods: In this prospective study, patients who were to undergo transesophageal echocardiography for various indications were screened. The study part...
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KARE Publishing
2019-01-01
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| Series: | Türk Kardiyoloji Derneği Arşivi |
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| Online Access: | https://jag.journalagent.com/z4/download_fulltext.asp?pdir=tkd&un=TKDA-04900 |
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| author | Leili Pourafkari Aidin Baghbani-oskouei Naser Aslanabadi Elgar Enamzadeh Samad Ghaffari Rezvaniyeh Salehi Bahram Sohrabi Safa Savadi-oskouei Arezou Tajlil Nader D Nader |
| author_facet | Leili Pourafkari Aidin Baghbani-oskouei Naser Aslanabadi Elgar Enamzadeh Samad Ghaffari Rezvaniyeh Salehi Bahram Sohrabi Safa Savadi-oskouei Arezou Tajlil Nader D Nader |
| author_sort | Leili Pourafkari |
| collection | DOAJ |
| description | Objective: The aim of this study was to examine the role of isolated rheumatic mitral stenosis (MS) in remodeling of the aorta at various locations.
Methods: In this prospective study, patients who were to undergo transesophageal echocardiography for various indications were screened. The study participants were classified into 2 groups according to the presence of MS with a valve area ≤1.5 cm2. Factors associated with the index dimensions of the aorta at the levels of the annulus, root, sinotubular junction (STJ), and the proximal ascending portion (5 cm from the annulus) were evaluated. Multivariate linear models were constructed including factors that affect the size of the aorta at any of the aforementioned levels. Pearson's correlation coefficient was used to investigate the association between mitral valve area, mitral valve gradient, and dimensions of the aorta.
Results: A total of 179 men and 354 women were enrolled. Eighty-four patients had MS (15.8%). The patients with MS were younger and less likely to have hypertension. In univariate analysis, patients with MS had a smaller annulus and STJ (p=0.003 and p=0.043, respectively). Multivariate analysis indicated that MS was correlated with a smaller indexed size of the aortic annulus, yielding a regression coefficient value of 0.541 (p=0.005).
Conclusion: The presence of significant stenosis at the level of the mitral valve is associated with a smaller diameter in the aortic annulus. It is yet to be clarified whether this phenomenon occurs due to chronic, long-standing, low stroke volume or involvement of the aortic annulus in the fibrotic process of mitral disease. |
| first_indexed | 2024-04-10T13:20:40Z |
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| id | doaj.art-c8d2618a001d4cd9bed9b1b969b732a2 |
| institution | Directory Open Access Journal |
| issn | 1016-5169 |
| language | English |
| last_indexed | 2024-04-10T13:20:40Z |
| publishDate | 2019-01-01 |
| publisher | KARE Publishing |
| record_format | Article |
| series | Türk Kardiyoloji Derneği Arşivi |
| spelling | doaj.art-c8d2618a001d4cd9bed9b1b969b732a22023-02-15T16:12:05ZengKARE PublishingTürk Kardiyoloji Derneği Arşivi1016-51692019-01-01471455210.5543/tkda.2018.04900TKDA-04900The association between severe mitral stenosis and the size of the aortic root and the ascending thoracic aortaLeili Pourafkari0Aidin Baghbani-oskouei1Naser Aslanabadi2Elgar Enamzadeh3Samad Ghaffari4Rezvaniyeh Salehi5Bahram Sohrabi6Safa Savadi-oskouei7Arezou Tajlil8Nader D Nader9Cardiovascular Research Center, Tabriz University of Medical Sciences, Tabriz, IranShahid Beheshti University of Medical Sciences, Tehran, IranCardiovascular Research Center, Tabriz University of Medical Sciences, Tabriz, IranCardiovascular Research Center, Tabriz University of Medical Sciences, Tabriz, IranCardiovascular Research Center, Tabriz University of Medical Sciences, Tabriz, IranCardiovascular Research Center, Tabriz University of Medical Sciences, Tabriz, IranCardiovascular Research Center, Tabriz University of Medical Sciences, Tabriz, IranCardiovascular Research Center, Tabriz University of Medical Sciences, Tabriz, IranCardiovascular Research Center, Tabriz University of Medical Sciences, Tabriz, IranDepartment of Anesthesiology, University at Buffalo, Buffalo, New York, USAObjective: The aim of this study was to examine the role of isolated rheumatic mitral stenosis (MS) in remodeling of the aorta at various locations. Methods: In this prospective study, patients who were to undergo transesophageal echocardiography for various indications were screened. The study participants were classified into 2 groups according to the presence of MS with a valve area ≤1.5 cm2. Factors associated with the index dimensions of the aorta at the levels of the annulus, root, sinotubular junction (STJ), and the proximal ascending portion (5 cm from the annulus) were evaluated. Multivariate linear models were constructed including factors that affect the size of the aorta at any of the aforementioned levels. Pearson's correlation coefficient was used to investigate the association between mitral valve area, mitral valve gradient, and dimensions of the aorta. Results: A total of 179 men and 354 women were enrolled. Eighty-four patients had MS (15.8%). The patients with MS were younger and less likely to have hypertension. In univariate analysis, patients with MS had a smaller annulus and STJ (p=0.003 and p=0.043, respectively). Multivariate analysis indicated that MS was correlated with a smaller indexed size of the aortic annulus, yielding a regression coefficient value of 0.541 (p=0.005). Conclusion: The presence of significant stenosis at the level of the mitral valve is associated with a smaller diameter in the aortic annulus. It is yet to be clarified whether this phenomenon occurs due to chronic, long-standing, low stroke volume or involvement of the aortic annulus in the fibrotic process of mitral disease.https://jag.journalagent.com/z4/download_fulltext.asp?pdir=tkd&un=TKDA-04900aortic annulusascending aortaechocardiography; mitral stenosis; rheumatic heart disease. |
| spellingShingle | Leili Pourafkari Aidin Baghbani-oskouei Naser Aslanabadi Elgar Enamzadeh Samad Ghaffari Rezvaniyeh Salehi Bahram Sohrabi Safa Savadi-oskouei Arezou Tajlil Nader D Nader The association between severe mitral stenosis and the size of the aortic root and the ascending thoracic aorta Türk Kardiyoloji Derneği Arşivi aortic annulus ascending aorta echocardiography; mitral stenosis; rheumatic heart disease. |
| title | The association between severe mitral stenosis and the size of the aortic root and the ascending thoracic aorta |
| title_full | The association between severe mitral stenosis and the size of the aortic root and the ascending thoracic aorta |
| title_fullStr | The association between severe mitral stenosis and the size of the aortic root and the ascending thoracic aorta |
| title_full_unstemmed | The association between severe mitral stenosis and the size of the aortic root and the ascending thoracic aorta |
| title_short | The association between severe mitral stenosis and the size of the aortic root and the ascending thoracic aorta |
| title_sort | association between severe mitral stenosis and the size of the aortic root and the ascending thoracic aorta |
| topic | aortic annulus ascending aorta echocardiography; mitral stenosis; rheumatic heart disease. |
| url | https://jag.journalagent.com/z4/download_fulltext.asp?pdir=tkd&un=TKDA-04900 |
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