The Alkyne Zipper Reaction: A Useful Tool in Synthetic Chemistry

The alkyne zipper reaction is an internal-to-terminal alkyne isomerization reaction with many interesting applications in synthetic chemistry, as it constitutes an efficient means of achieving acetylene functionalization. A review of its applications in synthesis processes is presented in this paper...

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Bibliographic Details
Main Authors: Åshild Moi Sørskår, Helge Ø. K. Stenstrøm, Yngve Stenstrøm, Simen Gjelseth Antonsen
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:Reactions
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Online Access:https://www.mdpi.com/2624-781X/4/1/2
Description
Summary:The alkyne zipper reaction is an internal-to-terminal alkyne isomerization reaction with many interesting applications in synthetic chemistry, as it constitutes an efficient means of achieving acetylene functionalization. A review of its applications in synthesis processes is presented in this paper, with a brief overview of the mechanistic features of the alkyne zipper reaction, as well as a brief overview of its future potential.
ISSN:2624-781X