The Alkyne Zipper Reaction: A Useful Tool in Synthetic Chemistry

The alkyne zipper reaction is an internal-to-terminal alkyne isomerization reaction with many interesting applications in synthetic chemistry, as it constitutes an efficient means of achieving acetylene functionalization. A review of its applications in synthesis processes is presented in this paper...

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Main Authors: Åshild Moi Sørskår, Helge Ø. K. Stenstrøm, Yngve Stenstrøm, Simen Gjelseth Antonsen
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:Reactions
Subjects:
Online Access:https://www.mdpi.com/2624-781X/4/1/2
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author Åshild Moi Sørskår
Helge Ø. K. Stenstrøm
Yngve Stenstrøm
Simen Gjelseth Antonsen
author_facet Åshild Moi Sørskår
Helge Ø. K. Stenstrøm
Yngve Stenstrøm
Simen Gjelseth Antonsen
author_sort Åshild Moi Sørskår
collection DOAJ
description The alkyne zipper reaction is an internal-to-terminal alkyne isomerization reaction with many interesting applications in synthetic chemistry, as it constitutes an efficient means of achieving acetylene functionalization. A review of its applications in synthesis processes is presented in this paper, with a brief overview of the mechanistic features of the alkyne zipper reaction, as well as a brief overview of its future potential.
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spelling doaj.art-c8d558e209064e4791e6facb52d30b6c2023-11-17T13:35:21ZengMDPI AGReactions2624-781X2022-12-0141266510.3390/reactions4010002The Alkyne Zipper Reaction: A Useful Tool in Synthetic ChemistryÅshild Moi Sørskår0Helge Ø. K. Stenstrøm1Yngve Stenstrøm2Simen Gjelseth Antonsen3Department of Mechanical, Electronic and Chemical Engineering, Faculty of Technology, Art and Design, Oslo Metropolitan University, NO-0130 Oslo, NorwayDepartment of Mechanical, Electronic and Chemical Engineering, Faculty of Technology, Art and Design, Oslo Metropolitan University, NO-0130 Oslo, NorwayDepartment of Chemistry Biotechnology and Food Science, Norwegian University of Life Science, NO-1433 Aas, NorwayDepartment of Mechanical, Electronic and Chemical Engineering, Faculty of Technology, Art and Design, Oslo Metropolitan University, NO-0130 Oslo, NorwayThe alkyne zipper reaction is an internal-to-terminal alkyne isomerization reaction with many interesting applications in synthetic chemistry, as it constitutes an efficient means of achieving acetylene functionalization. A review of its applications in synthesis processes is presented in this paper, with a brief overview of the mechanistic features of the alkyne zipper reaction, as well as a brief overview of its future potential.https://www.mdpi.com/2624-781X/4/1/2alkyne isomerizationacetylene isomerizationnatural product synthesiszipperalkyne chemistry
spellingShingle Åshild Moi Sørskår
Helge Ø. K. Stenstrøm
Yngve Stenstrøm
Simen Gjelseth Antonsen
The Alkyne Zipper Reaction: A Useful Tool in Synthetic Chemistry
Reactions
alkyne isomerization
acetylene isomerization
natural product synthesis
zipper
alkyne chemistry
title The Alkyne Zipper Reaction: A Useful Tool in Synthetic Chemistry
title_full The Alkyne Zipper Reaction: A Useful Tool in Synthetic Chemistry
title_fullStr The Alkyne Zipper Reaction: A Useful Tool in Synthetic Chemistry
title_full_unstemmed The Alkyne Zipper Reaction: A Useful Tool in Synthetic Chemistry
title_short The Alkyne Zipper Reaction: A Useful Tool in Synthetic Chemistry
title_sort alkyne zipper reaction a useful tool in synthetic chemistry
topic alkyne isomerization
acetylene isomerization
natural product synthesis
zipper
alkyne chemistry
url https://www.mdpi.com/2624-781X/4/1/2
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