Erythropoiesis and Red Cell Indices Undergo Adjustments during Pregnancy in Response to Maternal Body Size but not Inflammation

Erythropoiesis and Red Cell Indices Undergo Adjustments during Pregnancy in Response to Maternal Body Size but not Inflammation

During human pregnancy, iron requirements gradually increase, leading to higher amounts of erythropoietin (EPO) and reticulocytes, and changes in erythrocyte size and density. Women with pregestational obesity experience “obesity hypoferremia” during pregnancy, which alters iron homeostasis. In this...

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Bibliographic Details
Main Authors: Rodrigo Vega-Sánchez, Mari Cruz Tolentino-Dolores, Blanca Cerezo-Rodríguez, Georgette Chehaibar-Besil, María Eugenia Flores-Quijano
Format: Article
Language:English
Published: MDPI AG 2020-04-01
Series:Nutrients
Subjects:
erythropoietin
red cell indices
pregnancy
maternal obesity
inflammation
hepcidin
Online Access:https://www.mdpi.com/2072-6643/12/4/975

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