Simultaneous surgical treatment of primary ovarian carcinoid and carcinoid heart disease
The incidence of neuroendocrine tumors (NET) is 2.5–5 per 100 000 population. Up to 20% of patients with NET develop carcinoid syndrome (CS), and in 40–50% of those carcinoid heart disease (CHD) is reported (0.27 per 100 000 population per year) [1]. Development of CS and CHD is determined by numero...
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| Format: | Article |
| Language: | English |
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Termedia Publishing House
2022-12-01
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| Series: | Polish Journal of Thoracic and Cardiovascular Surgery |
| Online Access: | https://www.termedia.pl/Simultaneous-surgical-treatment-of-primary-ovarian-carcinoid-and-carcinoid-heart-disease,40,48519,1,1.html |
| _version_ | 1797943469462781952 |
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| author | Uladzimir Andrushchuk Aliaxandr Saevich Viktoria Ermochenko Mikalai Shchatsinka |
| author_facet | Uladzimir Andrushchuk Aliaxandr Saevich Viktoria Ermochenko Mikalai Shchatsinka |
| author_sort | Uladzimir Andrushchuk |
| collection | DOAJ |
| description | The incidence of neuroendocrine tumors (NET) is 2.5–5 per 100 000 population. Up to 20% of patients with NET develop carcinoid syndrome (CS), and in 40–50% of those carcinoid heart disease (CHD) is reported (0.27 per 100 000 population per year) [1]. Development of CS and CHD is determined by numerous vasoactive substances (serotonin, kallikrein, bradykinin, histamine, prostaglandins, etc.) which are produced by NET [2]. Primary ovarian carcinoid is a rare disease and accounts for 0.3–1.0% of all carcinoid tumors and up to 0.1% of ovarian tumors [3]. Venous drainage from ovaries, as from other paired organs, bypasses the liver and enters the vena cava inferior, which is the main reason for early development of CS and manifestation in ovarian carcinoids. Typical clinical symptoms of CS include flushing (90%), diarrhea (70%), wheezing (15%), fatigue, hypotension and arrhythmias [4]. Treatment of CS is a challenge due to often late diagnostics, life-threatening carcinoid crises and lack of established guidelines for surgical treatment of ovarian tumors, associated with CHD [5]. |
| first_indexed | 2024-04-10T20:24:40Z |
| format | Article |
| id | doaj.art-c8d8b72520bd4c8da4f71e9643cbb09c |
| institution | Directory Open Access Journal |
| issn | 1731-5530 1897-4252 |
| language | English |
| last_indexed | 2024-04-10T20:24:40Z |
| publishDate | 2022-12-01 |
| publisher | Termedia Publishing House |
| record_format | Article |
| series | Polish Journal of Thoracic and Cardiovascular Surgery |
| spelling | doaj.art-c8d8b72520bd4c8da4f71e9643cbb09c2023-01-25T13:25:32ZengTermedia Publishing HousePolish Journal of Thoracic and Cardiovascular Surgery1731-55301897-42522022-12-0119424925210.5114/kitp.2022.12209748519Simultaneous surgical treatment of primary ovarian carcinoid and carcinoid heart diseaseUladzimir AndrushchukAliaxandr SaevichViktoria ErmochenkoMikalai ShchatsinkaThe incidence of neuroendocrine tumors (NET) is 2.5–5 per 100 000 population. Up to 20% of patients with NET develop carcinoid syndrome (CS), and in 40–50% of those carcinoid heart disease (CHD) is reported (0.27 per 100 000 population per year) [1]. Development of CS and CHD is determined by numerous vasoactive substances (serotonin, kallikrein, bradykinin, histamine, prostaglandins, etc.) which are produced by NET [2]. Primary ovarian carcinoid is a rare disease and accounts for 0.3–1.0% of all carcinoid tumors and up to 0.1% of ovarian tumors [3]. Venous drainage from ovaries, as from other paired organs, bypasses the liver and enters the vena cava inferior, which is the main reason for early development of CS and manifestation in ovarian carcinoids. Typical clinical symptoms of CS include flushing (90%), diarrhea (70%), wheezing (15%), fatigue, hypotension and arrhythmias [4]. Treatment of CS is a challenge due to often late diagnostics, life-threatening carcinoid crises and lack of established guidelines for surgical treatment of ovarian tumors, associated with CHD [5].https://www.termedia.pl/Simultaneous-surgical-treatment-of-primary-ovarian-carcinoid-and-carcinoid-heart-disease,40,48519,1,1.html |
| spellingShingle | Uladzimir Andrushchuk Aliaxandr Saevich Viktoria Ermochenko Mikalai Shchatsinka Simultaneous surgical treatment of primary ovarian carcinoid and carcinoid heart disease Polish Journal of Thoracic and Cardiovascular Surgery |
| title | Simultaneous surgical treatment of primary ovarian carcinoid and carcinoid heart disease |
| title_full | Simultaneous surgical treatment of primary ovarian carcinoid and carcinoid heart disease |
| title_fullStr | Simultaneous surgical treatment of primary ovarian carcinoid and carcinoid heart disease |
| title_full_unstemmed | Simultaneous surgical treatment of primary ovarian carcinoid and carcinoid heart disease |
| title_short | Simultaneous surgical treatment of primary ovarian carcinoid and carcinoid heart disease |
| title_sort | simultaneous surgical treatment of primary ovarian carcinoid and carcinoid heart disease |
| url | https://www.termedia.pl/Simultaneous-surgical-treatment-of-primary-ovarian-carcinoid-and-carcinoid-heart-disease,40,48519,1,1.html |
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