Toxoplasma gondii infection in interstate truck drivers: a case–control seroprevalence study
Abstract Background Infection with Toxoplasma gondii can be acquired via the ingestion of undercooked or raw meat containing tissue cysts, or via ingestion of water contaminated with oocysts. Professional long distance truck driving may have epidemiological importance for food-borne infections since...
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| Format: | Article |
| Language: | English |
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BMC
2015-02-01
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| Series: | Parasites & Vectors |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s13071-015-0690-z |
| _version_ | 1797811780456546304 |
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| author | Cosme Alvarado-Esquivel Sandy Janet Pacheco-Vega Jesús Hernández-Tinoco Misael Salcedo-Jáquez Luis Francisco Sánchez-Anguiano Luis Omar Berumen-Segovia Elizabeth Rábago-Sánchez Oliver Liesenfeld |
| author_facet | Cosme Alvarado-Esquivel Sandy Janet Pacheco-Vega Jesús Hernández-Tinoco Misael Salcedo-Jáquez Luis Francisco Sánchez-Anguiano Luis Omar Berumen-Segovia Elizabeth Rábago-Sánchez Oliver Liesenfeld |
| author_sort | Cosme Alvarado-Esquivel |
| collection | DOAJ |
| description | Abstract Background Infection with Toxoplasma gondii can be acquired via the ingestion of undercooked or raw meat containing tissue cysts, or via ingestion of water contaminated with oocysts. Professional long distance truck driving may have epidemiological importance for food-borne infections since drivers eat out of home and in places where hygiene and cooking practices are uncertain. We aimed to determine whether interstate truck drivers in Durango, Mexico have an increased risk of infection with T. gondii as indicated by seropositivity; and to determine the socio-demographic, work, clinical, and behavioral characteristics associated with T. gondii seropositivity in interstate truck drivers. Methods Through a case–control study design, 192 truck drivers and 192 controls from the general population of the same region matched by gender and age were examined with enzyme-linked immunoassays for the presence of anti-Toxoplasma IgG and IgM antibodies. Socio-demographic, work, clinical and behavioral characteristics from the truck drivers were obtained. Results Anti-T. gondii IgG antibodies were found in 23 (12.0%) of 192 truck drivers and in 13 (6.8%) of 192 controls (OR = 21.0; 95% CI: 1.23-358.38; P = 0.002). Anti-T. gondii IgM antibodies were found in 7 (3.6%) cases and in 7 (3.6%) controls (P = 1.00). The seroprevalence of T. gondii infection was higher in drivers with reflex impairment than in those without this impairment (4/13, 30.8% vs 19/179, 10.6%, respectively; P = 0.05), and in drivers with hearing impairment than in those without this impairment (3/7, 42.9% vs 20/185, 10.8%, respectively; P = 0.03). Multivariate analysis of work and behavioral characteristics of truck drives showed positive associations of T. gondii exposure with trips to the south of Mexico (OR = 3.11; 95% CI: 1.02-9.44; P = 0.04) and consumption of horse meat (OR = 5.18; 95% CI: 1.62-16.55; P = 0.005). Conclusions Results suggest that interstate truck drivers may have an increased risk for T. gondii infection, and that T. gondii exposure may be impacting neurological functions in truck drivers. Contributing factors for T. gondii exposure should be taken into account for the design of optimal prevention measures against T. gondii infection. |
| first_indexed | 2024-03-13T07:28:47Z |
| format | Article |
| id | doaj.art-c8d940c3a05e4ff099e512094153f09b |
| institution | Directory Open Access Journal |
| issn | 1756-3305 |
| language | English |
| last_indexed | 2024-03-13T07:28:47Z |
| publishDate | 2015-02-01 |
| publisher | BMC |
| record_format | Article |
| series | Parasites & Vectors |
| spelling | doaj.art-c8d940c3a05e4ff099e512094153f09b2023-06-04T11:14:57ZengBMCParasites & Vectors1756-33052015-02-01811610.1186/s13071-015-0690-zToxoplasma gondii infection in interstate truck drivers: a case–control seroprevalence studyCosme Alvarado-Esquivel0Sandy Janet Pacheco-Vega1Jesús Hernández-Tinoco2Misael Salcedo-Jáquez3Luis Francisco Sánchez-Anguiano4Luis Omar Berumen-Segovia5Elizabeth Rábago-Sánchez6Oliver Liesenfeld7Faculty of Medicine and Nutrition, Juárez University of Durango StateFaculty of Medicine and Nutrition, Juárez University of Durango StateInstitute for Scientific Research “Dr. Roberto Rivera Damm”, Juárez University of Durango StateFaculty of Medicine and Nutrition, Juárez University of Durango StateInstitute for Scientific Research “Dr. Roberto Rivera Damm”, Juárez University of Durango StateFaculty of Medicine and Nutrition, Juárez University of Durango StateFaculty of Medicine and Nutrition, Juárez University of Durango StateInstitute for Microbiology and Hygiene, Campus Benjamin Franklin, Charité Medical SchoolAbstract Background Infection with Toxoplasma gondii can be acquired via the ingestion of undercooked or raw meat containing tissue cysts, or via ingestion of water contaminated with oocysts. Professional long distance truck driving may have epidemiological importance for food-borne infections since drivers eat out of home and in places where hygiene and cooking practices are uncertain. We aimed to determine whether interstate truck drivers in Durango, Mexico have an increased risk of infection with T. gondii as indicated by seropositivity; and to determine the socio-demographic, work, clinical, and behavioral characteristics associated with T. gondii seropositivity in interstate truck drivers. Methods Through a case–control study design, 192 truck drivers and 192 controls from the general population of the same region matched by gender and age were examined with enzyme-linked immunoassays for the presence of anti-Toxoplasma IgG and IgM antibodies. Socio-demographic, work, clinical and behavioral characteristics from the truck drivers were obtained. Results Anti-T. gondii IgG antibodies were found in 23 (12.0%) of 192 truck drivers and in 13 (6.8%) of 192 controls (OR = 21.0; 95% CI: 1.23-358.38; P = 0.002). Anti-T. gondii IgM antibodies were found in 7 (3.6%) cases and in 7 (3.6%) controls (P = 1.00). The seroprevalence of T. gondii infection was higher in drivers with reflex impairment than in those without this impairment (4/13, 30.8% vs 19/179, 10.6%, respectively; P = 0.05), and in drivers with hearing impairment than in those without this impairment (3/7, 42.9% vs 20/185, 10.8%, respectively; P = 0.03). Multivariate analysis of work and behavioral characteristics of truck drives showed positive associations of T. gondii exposure with trips to the south of Mexico (OR = 3.11; 95% CI: 1.02-9.44; P = 0.04) and consumption of horse meat (OR = 5.18; 95% CI: 1.62-16.55; P = 0.005). Conclusions Results suggest that interstate truck drivers may have an increased risk for T. gondii infection, and that T. gondii exposure may be impacting neurological functions in truck drivers. Contributing factors for T. gondii exposure should be taken into account for the design of optimal prevention measures against T. gondii infection.https://doi.org/10.1186/s13071-015-0690-zToxoplasma gondiiSeroprevalenceTruck driversCase–control studyRisk factors |
| spellingShingle | Cosme Alvarado-Esquivel Sandy Janet Pacheco-Vega Jesús Hernández-Tinoco Misael Salcedo-Jáquez Luis Francisco Sánchez-Anguiano Luis Omar Berumen-Segovia Elizabeth Rábago-Sánchez Oliver Liesenfeld Toxoplasma gondii infection in interstate truck drivers: a case–control seroprevalence study Parasites & Vectors Toxoplasma gondii Seroprevalence Truck drivers Case–control study Risk factors |
| title | Toxoplasma gondii infection in interstate truck drivers: a case–control seroprevalence study |
| title_full | Toxoplasma gondii infection in interstate truck drivers: a case–control seroprevalence study |
| title_fullStr | Toxoplasma gondii infection in interstate truck drivers: a case–control seroprevalence study |
| title_full_unstemmed | Toxoplasma gondii infection in interstate truck drivers: a case–control seroprevalence study |
| title_short | Toxoplasma gondii infection in interstate truck drivers: a case–control seroprevalence study |
| title_sort | toxoplasma gondii infection in interstate truck drivers a case control seroprevalence study |
| topic | Toxoplasma gondii Seroprevalence Truck drivers Case–control study Risk factors |
| url | https://doi.org/10.1186/s13071-015-0690-z |
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