Association of labour duration in spontaneous deliveries with low neonatal Apgar scores and foetal acidosis: the Japan Environment and Children’s Study
Abstract This study evaluated the association between labour duration (LD) and incidence of low neonatal Apgar scores and foetal acidosis. Data of 37,682 women with full-term singleton spontaneous vaginal deliveries from the Japan Environment and Children’s Study were analysed. Women were classified...
| Main Authors: | , , , , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Nature Portfolio
2022-12-01
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| Series: | Scientific Reports |
| Online Access: | https://doi.org/10.1038/s41598-022-24359-3 |
| _version_ | 1828265920718438400 |
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| author | Tsuyoshi Murata Shun Yasuda Karin Imaizumi Hirotaka Isogami Toma Fukuda Hyo Kyozuka Akiko Yamaguchi Akiko Sato Yuka Ogata Kosei Shinoki Mitsuaki Hosoya Seiji Yasumura Koichi Hashimoto Hidekazu Nishigori Keiya Fujimori The Japan Environment, Children’s Study (JECS) Group |
| author_facet | Tsuyoshi Murata Shun Yasuda Karin Imaizumi Hirotaka Isogami Toma Fukuda Hyo Kyozuka Akiko Yamaguchi Akiko Sato Yuka Ogata Kosei Shinoki Mitsuaki Hosoya Seiji Yasumura Koichi Hashimoto Hidekazu Nishigori Keiya Fujimori The Japan Environment, Children’s Study (JECS) Group |
| author_sort | Tsuyoshi Murata |
| collection | DOAJ |
| description | Abstract This study evaluated the association between labour duration (LD) and incidence of low neonatal Apgar scores and foetal acidosis. Data of 37,682 women with full-term singleton spontaneous vaginal deliveries from the Japan Environment and Children’s Study were analysed. Women were classified according to the median LD as nulliparous (< 10 or ≥ 10 h) or multiparous (< 5 or ≥ 5 h) and further into five subcategories: nulliparous (< 10.0, 10.0–12.9, 13.0–15.9, 16.0–18.9, and ≥ 19 h) and multiparous (< 5.0, 5.0–7.9, 8.0–10.9, 11.0–13.9, and ≥ 14.0 h). Multiple logistic regression models were used to determine odds ratios (ORs) for outcomes in women with over-median LD. Over-median LD exhibited no statistically significant association with low neonatal Apgar scores. The adjusted ORs for both umbilical artery (UmA-pH) < 7.2 and < 7.1 were increased in nulliparous women with over-median LD, whereas only the adjusted OR for UmA-pH < 7.2 was increased in multiparous women with over-median LD. Moreover, this association manifested as a plateau in nulliparous women with LD ≥ 13 h and without dose-dependent association in multiparous women. |
| first_indexed | 2024-04-13T04:45:24Z |
| format | Article |
| id | doaj.art-c8dedc62b6594738aa37477335e35fae |
| institution | Directory Open Access Journal |
| issn | 2045-2322 |
| language | English |
| last_indexed | 2024-04-13T04:45:24Z |
| publishDate | 2022-12-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Scientific Reports |
| spelling | doaj.art-c8dedc62b6594738aa37477335e35fae2022-12-22T03:01:51ZengNature PortfolioScientific Reports2045-23222022-12-011211910.1038/s41598-022-24359-3Association of labour duration in spontaneous deliveries with low neonatal Apgar scores and foetal acidosis: the Japan Environment and Children’s StudyTsuyoshi Murata0Shun Yasuda1Karin Imaizumi2Hirotaka Isogami3Toma Fukuda4Hyo Kyozuka5Akiko Yamaguchi6Akiko Sato7Yuka Ogata8Kosei Shinoki9Mitsuaki Hosoya10Seiji Yasumura11Koichi Hashimoto12Hidekazu Nishigori13Keiya Fujimori14The Japan Environment, Children’s Study (JECS) GroupFukushima Regional Center for the Japan Environment and Children’s StudyFukushima Regional Center for the Japan Environment and Children’s StudyFukushima Regional Center for the Japan Environment and Children’s StudyFukushima Regional Center for the Japan Environment and Children’s StudyFukushima Regional Center for the Japan Environment and Children’s StudyFukushima Regional Center for the Japan Environment and Children’s StudyFukushima Regional Center for the Japan Environment and Children’s StudyFukushima Regional Center for the Japan Environment and Children’s StudyFukushima Regional Center for the Japan Environment and Children’s StudyFukushima Regional Center for the Japan Environment and Children’s StudyFukushima Regional Center for the Japan Environment and Children’s StudyFukushima Regional Center for the Japan Environment and Children’s StudyFukushima Regional Center for the Japan Environment and Children’s StudyFukushima Regional Center for the Japan Environment and Children’s StudyFukushima Regional Center for the Japan Environment and Children’s StudyAbstract This study evaluated the association between labour duration (LD) and incidence of low neonatal Apgar scores and foetal acidosis. Data of 37,682 women with full-term singleton spontaneous vaginal deliveries from the Japan Environment and Children’s Study were analysed. Women were classified according to the median LD as nulliparous (< 10 or ≥ 10 h) or multiparous (< 5 or ≥ 5 h) and further into five subcategories: nulliparous (< 10.0, 10.0–12.9, 13.0–15.9, 16.0–18.9, and ≥ 19 h) and multiparous (< 5.0, 5.0–7.9, 8.0–10.9, 11.0–13.9, and ≥ 14.0 h). Multiple logistic regression models were used to determine odds ratios (ORs) for outcomes in women with over-median LD. Over-median LD exhibited no statistically significant association with low neonatal Apgar scores. The adjusted ORs for both umbilical artery (UmA-pH) < 7.2 and < 7.1 were increased in nulliparous women with over-median LD, whereas only the adjusted OR for UmA-pH < 7.2 was increased in multiparous women with over-median LD. Moreover, this association manifested as a plateau in nulliparous women with LD ≥ 13 h and without dose-dependent association in multiparous women.https://doi.org/10.1038/s41598-022-24359-3 |
| spellingShingle | Tsuyoshi Murata Shun Yasuda Karin Imaizumi Hirotaka Isogami Toma Fukuda Hyo Kyozuka Akiko Yamaguchi Akiko Sato Yuka Ogata Kosei Shinoki Mitsuaki Hosoya Seiji Yasumura Koichi Hashimoto Hidekazu Nishigori Keiya Fujimori The Japan Environment, Children’s Study (JECS) Group Association of labour duration in spontaneous deliveries with low neonatal Apgar scores and foetal acidosis: the Japan Environment and Children’s Study Scientific Reports |
| title | Association of labour duration in spontaneous deliveries with low neonatal Apgar scores and foetal acidosis: the Japan Environment and Children’s Study |
| title_full | Association of labour duration in spontaneous deliveries with low neonatal Apgar scores and foetal acidosis: the Japan Environment and Children’s Study |
| title_fullStr | Association of labour duration in spontaneous deliveries with low neonatal Apgar scores and foetal acidosis: the Japan Environment and Children’s Study |
| title_full_unstemmed | Association of labour duration in spontaneous deliveries with low neonatal Apgar scores and foetal acidosis: the Japan Environment and Children’s Study |
| title_short | Association of labour duration in spontaneous deliveries with low neonatal Apgar scores and foetal acidosis: the Japan Environment and Children’s Study |
| title_sort | association of labour duration in spontaneous deliveries with low neonatal apgar scores and foetal acidosis the japan environment and children s study |
| url | https://doi.org/10.1038/s41598-022-24359-3 |
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