Solid-State Dehydration Mechanism of Diclofenac Sodium Salt Hydrates

Solid-State Dehydration Mechanism of Diclofenac Sodium Salt Hydrates

Salt formation is a useful technique for improving the solubility of active pharmaceutical ingredients (APIs). For instance, a nonsteroidal anti-inflammatory drug, diclofenac (DIC), is used in a sodium salt form, and it has been reported to form several hydrate forms. However, the crystal structure...

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Bibliographic Details
Main Authors:	Hironaga Oyama, Takashi Miyamoto, Akiko Sekine, Ilma Nugrahani, Hidehiro Uekusa
Format:	Article
Language:	English
Published:	MDPI AG 2021-04-01
Series:	Crystals
Subjects:	crystal structure analysis diclofenac diclofenac sodium hydration–dehydration mechanism hydrate anhydrate
Online Access:	https://www.mdpi.com/2073-4352/11/4/412

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