Single cell analysis of short-term dry eye induced changes in cornea immune cell populations

Single cell analysis of short-term dry eye induced changes in cornea immune cell populations

BackgroundDry eye causes corneal inflammation, epitheliopathy and sensorineural changes. This study evaluates the hypothesis that dry eye alters the percentages and transcriptional profiles of immune cell populations in the cornea.MethodsDesiccating stress (DS) induced dry eye was created by pharmac...

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Bibliographic Details
Main Authors:	Jehan Alam, Ebru Yaman, Gerda Cristal Villalba Silva, Rui Chen, Cinita S. de Paiva, Mary Ann Stepp, Stephen C. Pflugfelder
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2024-03-01
Series:	Frontiers in Medicine
Subjects:	dry eye macrophage cornea nerve innate inflammation CXCL1
Online Access:	https://www.frontiersin.org/articles/10.3389/fmed.2024.1362336/full

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