Mechanisms of the action of adenine on anti‐allergic effects in mast cells

Mechanisms of the action of adenine on anti‐allergic effects in mast cells

Abstract Introduction Mast cells play an important role in allergic responses. Methods We herein demonstrated the mechanisms of inhibitory effect of adenine on IgE/antigen‐induced degranulation and TNF‐α release in mast cells. Results We found that these effects were dependent on the amino group of...

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Bibliographic Details
Main Authors: Toru Hosoi, Shinsuke Ino, Fumie Ohnishi, Kenichi Todoroki, Michiko Yoshii, Mai Kakimoto, Christa E. Müller, Koichiro Ozawa
Format: Article
Language:English
Published: Wiley 2018-03-01
Series:Immunity, Inflammation and Disease
Subjects:
adenine
mast cells
allergy
Online Access:https://doi.org/10.1002/iid3.200

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