Study the Antifungal and Ocular Permeation of Ketoconazole from Ophthalmic Formulations Containing Trans-Ethosomes Nanoparticles

Study the Antifungal and Ocular Permeation of Ketoconazole from Ophthalmic Formulations Containing Trans-Ethosomes Nanoparticles

Ketoconazole (KET), a synthetic imidazole broad-spectrum antifungal agent, is characterized by its poor aqueous solubility and high molecular weight, which might hamper its corneal permeation. The aim was to develop an ophthalmic formulation loaded with optimized trans-ethosomal vesicles to enhance...

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Bibliographic Details
Main Authors: Tarek A. Ahmed, Maram M. Alzahrani, Alaa Sirwi, Nabil A. Alhakamy
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:Pharmaceutics
Subjects:
ketoconazole
trans-ethosomes
optimization
in situ gel
antifungal
ocular permeation
Online Access:https://www.mdpi.com/1999-4923/13/2/151

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