PLGA nanoparticles as a platform for vitamin D-based cancer therapy

PLGA nanoparticles as a platform for vitamin D-based cancer therapy

Poly(lactic-co-glycolic acid) (PLGA) nanoparticles were studied as drug delivery vehicles for calcitriol, the active form of vitamin D3. In vitro effects of calcitriol encapsulated in PLGA nanoparticles were evaluated with respect to free calcitriol on human pancreatic cell lines, S2-013 and hTERT-H...

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Bibliographic Details
Main Authors: Maria J. Ramalho, Joana A. Loureiro, Bárbara Gomes, Manuela F. Frasco, Manuel A. N. Coelho, M. Carmo Pereira
Format: Article
Language:English
Published: Beilstein-Institut 2015-06-01
Series:Beilstein Journal of Nanotechnology
Subjects:
1α,25-dihydroxyvitamin D3
calcitriol
cancer therapy
drug delivery
poly(lactic-co-glycolic acid)
Online Access:https://doi.org/10.3762/bjnano.6.135

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