The Immunotherapy for Colorectal Cancer, Lung Cancer and Pancreatic Cancer
Immunotherapy is a novel anti-cancer method which employs a different mechanism to conventional treatment. It has become a significant strategy because it provides a better or an alternative option for cancer patients. Recently, immunotherapy has been increasingly approved for the treatment of cance...
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2021-11-01
|
| Series: | International Journal of Molecular Sciences |
| Subjects: | |
| Online Access: | https://www.mdpi.com/1422-0067/22/23/12836 |
| _version_ | 1797507810127249408 |
|---|---|
| author | Shiu-Jau Chen Shao-Cheng Wang Yuan-Chuan Chen |
| author_facet | Shiu-Jau Chen Shao-Cheng Wang Yuan-Chuan Chen |
| author_sort | Shiu-Jau Chen |
| collection | DOAJ |
| description | Immunotherapy is a novel anti-cancer method which employs a different mechanism to conventional treatment. It has become a significant strategy because it provides a better or an alternative option for cancer patients. Recently, immunotherapy has been increasingly approved for the treatment of cancer; however, it has various limitations; for instance, it is only suitable for specific patients, the response rate is still low in most cases, etc. Colorectal cancer, lung cancer and pancreatic cancer are known as three major death-causing cancers in most countries. In this review, we discuss immunotherapeutic treatment for these three cancers, and consider the option, prospects and limitations of immunotherapy. The development of immunotherapy should focus on the discovery of biomarkers to screen suitable patients, new targets on tumors, neoadjuvant immunotherapy and the combination of immunotherapy with conventional therapeutic methods. We can expect that immunotherapy potentially will develop as one of the best therapies for patients with advanced cancer or poor responses to traditional methods. |
| first_indexed | 2024-03-10T04:53:40Z |
| format | Article |
| id | doaj.art-c8e6176ff4c6451ead762cf9ad7c984e |
| institution | Directory Open Access Journal |
| issn | 1661-6596 1422-0067 |
| language | English |
| last_indexed | 2024-03-10T04:53:40Z |
| publishDate | 2021-11-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | International Journal of Molecular Sciences |
| spelling | doaj.art-c8e6176ff4c6451ead762cf9ad7c984e2023-11-23T02:28:52ZengMDPI AGInternational Journal of Molecular Sciences1661-65961422-00672021-11-0122231283610.3390/ijms222312836The Immunotherapy for Colorectal Cancer, Lung Cancer and Pancreatic CancerShiu-Jau Chen0Shao-Cheng Wang1Yuan-Chuan Chen2Department of Neurosurgery, Mackay Memorial Hospital, Taipei 104217, TaiwanDepartment of Psychiatric, Taoyuan General Hospital, Ministry of Health and Welfare, Taoyuan 33004, TaiwanJenteh Junior College of Medicine, Nursing and Management, Hou-Loung Town, Miaoli County 35664, TaiwanImmunotherapy is a novel anti-cancer method which employs a different mechanism to conventional treatment. It has become a significant strategy because it provides a better or an alternative option for cancer patients. Recently, immunotherapy has been increasingly approved for the treatment of cancer; however, it has various limitations; for instance, it is only suitable for specific patients, the response rate is still low in most cases, etc. Colorectal cancer, lung cancer and pancreatic cancer are known as three major death-causing cancers in most countries. In this review, we discuss immunotherapeutic treatment for these three cancers, and consider the option, prospects and limitations of immunotherapy. The development of immunotherapy should focus on the discovery of biomarkers to screen suitable patients, new targets on tumors, neoadjuvant immunotherapy and the combination of immunotherapy with conventional therapeutic methods. We can expect that immunotherapy potentially will develop as one of the best therapies for patients with advanced cancer or poor responses to traditional methods.https://www.mdpi.com/1422-0067/22/23/12836colorectal cancerlung cancerpancreatic cancerimmunotherapyimmune checkpointmonoclonal antibody |
| spellingShingle | Shiu-Jau Chen Shao-Cheng Wang Yuan-Chuan Chen The Immunotherapy for Colorectal Cancer, Lung Cancer and Pancreatic Cancer International Journal of Molecular Sciences colorectal cancer lung cancer pancreatic cancer immunotherapy immune checkpoint monoclonal antibody |
| title | The Immunotherapy for Colorectal Cancer, Lung Cancer and Pancreatic Cancer |
| title_full | The Immunotherapy for Colorectal Cancer, Lung Cancer and Pancreatic Cancer |
| title_fullStr | The Immunotherapy for Colorectal Cancer, Lung Cancer and Pancreatic Cancer |
| title_full_unstemmed | The Immunotherapy for Colorectal Cancer, Lung Cancer and Pancreatic Cancer |
| title_short | The Immunotherapy for Colorectal Cancer, Lung Cancer and Pancreatic Cancer |
| title_sort | immunotherapy for colorectal cancer lung cancer and pancreatic cancer |
| topic | colorectal cancer lung cancer pancreatic cancer immunotherapy immune checkpoint monoclonal antibody |
| url | https://www.mdpi.com/1422-0067/22/23/12836 |
| work_keys_str_mv | AT shiujauchen theimmunotherapyforcolorectalcancerlungcancerandpancreaticcancer AT shaochengwang theimmunotherapyforcolorectalcancerlungcancerandpancreaticcancer AT yuanchuanchen theimmunotherapyforcolorectalcancerlungcancerandpancreaticcancer AT shiujauchen immunotherapyforcolorectalcancerlungcancerandpancreaticcancer AT shaochengwang immunotherapyforcolorectalcancerlungcancerandpancreaticcancer AT yuanchuanchen immunotherapyforcolorectalcancerlungcancerandpancreaticcancer |