N-terminal peptide fragment constitutes core of amyloid deposition of serum amyloid A: An imaging mass spectrometry study

N-terminal peptide fragment constitutes core of amyloid deposition of serum amyloid A: An imaging mass spectrometry study

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Serum amyloid A (SAA) is an acute phase protein, which undergoes structural changes and deposits in the extracellular matrix, causing organ damage. Systemic AA amyloidosis is a relatively common amyloid subtype among the more than 30 amyloid subtypes, but the mechanism of amyloid fibril formation re...

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Bibliographic Details
Main Authors: Yukako Shintani-Domoto, Yuki Sugiura, Makiko Ogawa, Eiji Sugiyama, Hiroyuki Abe, Takashi Sakatani, Ryuji Ohashi, Tetsuo Ushiku, Masashi Fukayama
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9565386/?tool=EBI

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