Exploring the Application of Graphene Oxide-Based Nanomaterials in the Repair of Osteoporotic Fractures
Osteoporotic fractures are induced by osteoporosis, which may lead to the degradation of bone tissues and microstructures and impair their healing ability. Conventional internal fixation therapies are ineffective in the treatment of osteoporotic fractures. Hence, developing tissue engineering materi...
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| Format: | Article |
| Language: | English |
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MDPI AG
2024-03-01
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| Series: | Nanomaterials |
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| Online Access: | https://www.mdpi.com/2079-4991/14/6/553 |
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| author | Hongfa Zhou Jinyuan Chen Xuan Zhang JingJing Chen Jiayou Chen Shicheng Jia Deli Wang Hui Zeng Jian Weng Fei Yu |
| author_facet | Hongfa Zhou Jinyuan Chen Xuan Zhang JingJing Chen Jiayou Chen Shicheng Jia Deli Wang Hui Zeng Jian Weng Fei Yu |
| author_sort | Hongfa Zhou |
| collection | DOAJ |
| description | Osteoporotic fractures are induced by osteoporosis, which may lead to the degradation of bone tissues and microstructures and impair their healing ability. Conventional internal fixation therapies are ineffective in the treatment of osteoporotic fractures. Hence, developing tissue engineering materials is crucial for repairing osteoporotic fractures. It has been demonstrated that nanomaterials, particularly graphene oxide (GO), possess unique advantages in tissue engineering due to their excellent biocompatibility, mechanical properties, and osteoinductive abilities. Based on that, GO-nanocomposites have garnered significant attention and hold promising prospects for bone repair applications. This paper provides a comprehensive insight into the properties of GO, preparation methods for nanocomposites, advantages of these materials, and relevant mechanisms for osteoporotic fracture applications. |
| first_indexed | 2024-04-24T17:57:34Z |
| format | Article |
| id | doaj.art-c8ee87a4ae8c44d4841a837afd8789a9 |
| institution | Directory Open Access Journal |
| issn | 2079-4991 |
| language | English |
| last_indexed | 2024-04-24T17:57:34Z |
| publishDate | 2024-03-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Nanomaterials |
| spelling | doaj.art-c8ee87a4ae8c44d4841a837afd8789a92024-03-27T13:57:40ZengMDPI AGNanomaterials2079-49912024-03-0114655310.3390/nano14060553Exploring the Application of Graphene Oxide-Based Nanomaterials in the Repair of Osteoporotic FracturesHongfa Zhou0Jinyuan Chen1Xuan Zhang2JingJing Chen3Jiayou Chen4Shicheng Jia5Deli Wang6Hui Zeng7Jian Weng8Fei Yu9Department of Bone & Joint Surgery, Peking University Shenzhen Hospital, Shenzhen 518036, ChinaDepartment of Bone & Joint Surgery, Peking University Shenzhen Hospital, Shenzhen 518036, ChinaDepartment of Bone & Joint Surgery, Peking University Shenzhen Hospital, Shenzhen 518036, ChinaMedical College, Shantou University, Shantou 515063, ChinaMedical College, Shantou University, Shantou 515063, ChinaMedical College, Shantou University, Shantou 515063, ChinaDepartment of Bone & Joint Surgery, Peking University Shenzhen Hospital, Shenzhen 518036, ChinaDepartment of Orthopedics, Shenzhen Second People’s Hospital, Shenzhen 518000, ChinaDepartment of Bone & Joint Surgery, Peking University Shenzhen Hospital, Shenzhen 518036, ChinaDepartment of Bone & Joint Surgery, Peking University Shenzhen Hospital, Shenzhen 518036, ChinaOsteoporotic fractures are induced by osteoporosis, which may lead to the degradation of bone tissues and microstructures and impair their healing ability. Conventional internal fixation therapies are ineffective in the treatment of osteoporotic fractures. Hence, developing tissue engineering materials is crucial for repairing osteoporotic fractures. It has been demonstrated that nanomaterials, particularly graphene oxide (GO), possess unique advantages in tissue engineering due to their excellent biocompatibility, mechanical properties, and osteoinductive abilities. Based on that, GO-nanocomposites have garnered significant attention and hold promising prospects for bone repair applications. This paper provides a comprehensive insight into the properties of GO, preparation methods for nanocomposites, advantages of these materials, and relevant mechanisms for osteoporotic fracture applications.https://www.mdpi.com/2079-4991/14/6/553graphene oxidenanomaterialosteoporotic fractures |
| spellingShingle | Hongfa Zhou Jinyuan Chen Xuan Zhang JingJing Chen Jiayou Chen Shicheng Jia Deli Wang Hui Zeng Jian Weng Fei Yu Exploring the Application of Graphene Oxide-Based Nanomaterials in the Repair of Osteoporotic Fractures Nanomaterials graphene oxide nanomaterial osteoporotic fractures |
| title | Exploring the Application of Graphene Oxide-Based Nanomaterials in the Repair of Osteoporotic Fractures |
| title_full | Exploring the Application of Graphene Oxide-Based Nanomaterials in the Repair of Osteoporotic Fractures |
| title_fullStr | Exploring the Application of Graphene Oxide-Based Nanomaterials in the Repair of Osteoporotic Fractures |
| title_full_unstemmed | Exploring the Application of Graphene Oxide-Based Nanomaterials in the Repair of Osteoporotic Fractures |
| title_short | Exploring the Application of Graphene Oxide-Based Nanomaterials in the Repair of Osteoporotic Fractures |
| title_sort | exploring the application of graphene oxide based nanomaterials in the repair of osteoporotic fractures |
| topic | graphene oxide nanomaterial osteoporotic fractures |
| url | https://www.mdpi.com/2079-4991/14/6/553 |
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