The diagnostic, prognostic role and molecular mechanism of miR-328 in human cancer
MicroRNA are non-coding small RNAs that bind to their target mRNA and cause mRNA degradation or translation inhibition. MiRNA dysregulation is linked to a variety of human cancers and has a role in the genesis and development of cancer pathology. MiR-328 has been reported to be involved in various h...
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2023-01-01
|
| Series: | Biomedicine & Pharmacotherapy |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S0753332222014202 |
| _version_ | 1811178886483935232 |
|---|---|
| author | Zhichao Wang Wenjie Xie Hongzai Guan |
| author_facet | Zhichao Wang Wenjie Xie Hongzai Guan |
| author_sort | Zhichao Wang |
| collection | DOAJ |
| description | MicroRNA are non-coding small RNAs that bind to their target mRNA and cause mRNA degradation or translation inhibition. MiRNA dysregulation is linked to a variety of human cancers and has a role in the genesis and development of cancer pathology. MiR-328 has been reported to be involved in various human cancers. And miR-328 is considered a key regulator in human cancer. It participates in biological processes such as proliferation, apoptosis, invasion, migration, and EMT. The present review will combine the basic and clinical studies to find that miR-328 promotes tumorigenesis and metastasis in human cancer. And we will describe the diagnostic, prognostic, and therapeutic value of miR-328 in various human cancers. |
| first_indexed | 2024-04-11T06:26:36Z |
| format | Article |
| id | doaj.art-c8f1b399338745dc958677af77d462e0 |
| institution | Directory Open Access Journal |
| issn | 0753-3322 |
| language | English |
| last_indexed | 2024-04-11T06:26:36Z |
| publishDate | 2023-01-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Biomedicine & Pharmacotherapy |
| spelling | doaj.art-c8f1b399338745dc958677af77d462e02022-12-22T04:40:21ZengElsevierBiomedicine & Pharmacotherapy0753-33222023-01-01157114031The diagnostic, prognostic role and molecular mechanism of miR-328 in human cancerZhichao Wang0Wenjie Xie1Hongzai Guan2Department of Clinical Laboratory, The Affiliated Hospital of Qingdao University, 16 Jiangsu Road, Qingdao 266003, ChinaDepartment of Clinical Laboratory, The Affiliated Hospital of Qingdao University, 16 Jiangsu Road, Qingdao 266003, ChinaCorresponding author.; Department of Clinical Laboratory, The Affiliated Hospital of Qingdao University, 16 Jiangsu Road, Qingdao 266003, ChinaMicroRNA are non-coding small RNAs that bind to their target mRNA and cause mRNA degradation or translation inhibition. MiRNA dysregulation is linked to a variety of human cancers and has a role in the genesis and development of cancer pathology. MiR-328 has been reported to be involved in various human cancers. And miR-328 is considered a key regulator in human cancer. It participates in biological processes such as proliferation, apoptosis, invasion, migration, and EMT. The present review will combine the basic and clinical studies to find that miR-328 promotes tumorigenesis and metastasis in human cancer. And we will describe the diagnostic, prognostic, and therapeutic value of miR-328 in various human cancers.http://www.sciencedirect.com/science/article/pii/S0753332222014202MiR-328CancerBiomarkerMechanismTumor suppressor |
| spellingShingle | Zhichao Wang Wenjie Xie Hongzai Guan The diagnostic, prognostic role and molecular mechanism of miR-328 in human cancer Biomedicine & Pharmacotherapy MiR-328 Cancer Biomarker Mechanism Tumor suppressor |
| title | The diagnostic, prognostic role and molecular mechanism of miR-328 in human cancer |
| title_full | The diagnostic, prognostic role and molecular mechanism of miR-328 in human cancer |
| title_fullStr | The diagnostic, prognostic role and molecular mechanism of miR-328 in human cancer |
| title_full_unstemmed | The diagnostic, prognostic role and molecular mechanism of miR-328 in human cancer |
| title_short | The diagnostic, prognostic role and molecular mechanism of miR-328 in human cancer |
| title_sort | diagnostic prognostic role and molecular mechanism of mir 328 in human cancer |
| topic | MiR-328 Cancer Biomarker Mechanism Tumor suppressor |
| url | http://www.sciencedirect.com/science/article/pii/S0753332222014202 |
| work_keys_str_mv | AT zhichaowang thediagnosticprognosticroleandmolecularmechanismofmir328inhumancancer AT wenjiexie thediagnosticprognosticroleandmolecularmechanismofmir328inhumancancer AT hongzaiguan thediagnosticprognosticroleandmolecularmechanismofmir328inhumancancer AT zhichaowang diagnosticprognosticroleandmolecularmechanismofmir328inhumancancer AT wenjiexie diagnosticprognosticroleandmolecularmechanismofmir328inhumancancer AT hongzaiguan diagnosticprognosticroleandmolecularmechanismofmir328inhumancancer |