Hypnotics use in children 0–18 months: moderate agreement between mother-reported survey data and prescription registry data

Background Different methods in pharmacoepidemiology can be used to study hypnotic use in children. But neither questionnaire-based data nor prescription records can be considered a “gold standard”. This study aimed to investigate the agreement between mother-reported questionnaire-based data and pr...

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Main Authors: Ingvild Holdø, Jørgen G. Bramness, Marte Handal, Leila Torgersen, Ted Reichborn-Kjennerud, Eivind Ystrøm, Hedvig Nordeng, Svetlana Skurtveit
Format: Article
Language:English
Published: Taylor & Francis Group 2017-12-01
Series:Journal of Pharmaceutical Policy and Practice
Subjects:
Online Access:http://dx.doi.org/10.1186/s40545-017-0117-7
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author Ingvild Holdø
Jørgen G. Bramness
Marte Handal
Leila Torgersen
Ted Reichborn-Kjennerud
Eivind Ystrøm
Hedvig Nordeng
Svetlana Skurtveit
author_facet Ingvild Holdø
Jørgen G. Bramness
Marte Handal
Leila Torgersen
Ted Reichborn-Kjennerud
Eivind Ystrøm
Hedvig Nordeng
Svetlana Skurtveit
author_sort Ingvild Holdø
collection DOAJ
description Background Different methods in pharmacoepidemiology can be used to study hypnotic use in children. But neither questionnaire-based data nor prescription records can be considered a “gold standard”. This study aimed to investigate the agreement between mother-reported questionnaire-based data and prescription record data for hypnotic drugs in children aged 0–18 months. The agreement was compared to the agreement for a group of antiepileptic drugs. Methods Prescription record data were collected from the Norwegian prescription database for 47,413 children also surveyed in the Norwegian mother and child cohort between 2005 and 2009. Agreement between in the two data sources was calculated using Cohens Kappa. Multinomial logistic regression was used to calculate the effect of sociodemographic variables on discrepancies in data sources. Results The agreement between mother-reported and dispensed hypnotics was less than 50% for all hypnotics. Sensitivity of reporting increased with number of filled prescriptions. The agreement of antiepileptic drugs was 92.9% in the same population. Of several sociodemographic factors only paternal educational level and maternal work situation was significantly related to agreement between prescription record and survey data. Conclusion There was a moderate agreement between reported use and dispensed hypnotic drugs for infants and toddlers. Results indicate that sociodemographic factors play only a minor role in explaining discrepancy.
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spelling doaj.art-c8f5132cd19e4d90876ea42c5c5005072023-12-07T15:28:01ZengTaylor & Francis GroupJournal of Pharmaceutical Policy and Practice2052-32112017-12-0110110.1186/s40545-017-0117-712315047Hypnotics use in children 0–18 months: moderate agreement between mother-reported survey data and prescription registry dataIngvild Holdø0Jørgen G. Bramness1Marte Handal2Leila Torgersen3Ted Reichborn-Kjennerud4Eivind Ystrøm5Hedvig Nordeng6Svetlana Skurtveit7Norwegian Centre of Addiction Research (SERAF),Norwegian National Advisory Unit on Concurrent Substance Abuse and Mental Health Disorders,Domain of Mental and Physical health,Domain of Mental and Physical health,Domain of Mental and Physical health,Domain of Mental and Physical health,Domain of Mental and Physical health,Norwegian Centre of Addiction Research (SERAF),Background Different methods in pharmacoepidemiology can be used to study hypnotic use in children. But neither questionnaire-based data nor prescription records can be considered a “gold standard”. This study aimed to investigate the agreement between mother-reported questionnaire-based data and prescription record data for hypnotic drugs in children aged 0–18 months. The agreement was compared to the agreement for a group of antiepileptic drugs. Methods Prescription record data were collected from the Norwegian prescription database for 47,413 children also surveyed in the Norwegian mother and child cohort between 2005 and 2009. Agreement between in the two data sources was calculated using Cohens Kappa. Multinomial logistic regression was used to calculate the effect of sociodemographic variables on discrepancies in data sources. Results The agreement between mother-reported and dispensed hypnotics was less than 50% for all hypnotics. Sensitivity of reporting increased with number of filled prescriptions. The agreement of antiepileptic drugs was 92.9% in the same population. Of several sociodemographic factors only paternal educational level and maternal work situation was significantly related to agreement between prescription record and survey data. Conclusion There was a moderate agreement between reported use and dispensed hypnotic drugs for infants and toddlers. Results indicate that sociodemographic factors play only a minor role in explaining discrepancy.http://dx.doi.org/10.1186/s40545-017-0117-7mobahypnotics and sedativesagreementchildprescriptions
spellingShingle Ingvild Holdø
Jørgen G. Bramness
Marte Handal
Leila Torgersen
Ted Reichborn-Kjennerud
Eivind Ystrøm
Hedvig Nordeng
Svetlana Skurtveit
Hypnotics use in children 0–18 months: moderate agreement between mother-reported survey data and prescription registry data
Journal of Pharmaceutical Policy and Practice
moba
hypnotics and sedatives
agreement
child
prescriptions
title Hypnotics use in children 0–18 months: moderate agreement between mother-reported survey data and prescription registry data
title_full Hypnotics use in children 0–18 months: moderate agreement between mother-reported survey data and prescription registry data
title_fullStr Hypnotics use in children 0–18 months: moderate agreement between mother-reported survey data and prescription registry data
title_full_unstemmed Hypnotics use in children 0–18 months: moderate agreement between mother-reported survey data and prescription registry data
title_short Hypnotics use in children 0–18 months: moderate agreement between mother-reported survey data and prescription registry data
title_sort hypnotics use in children 0 18 months moderate agreement between mother reported survey data and prescription registry data
topic moba
hypnotics and sedatives
agreement
child
prescriptions
url http://dx.doi.org/10.1186/s40545-017-0117-7
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