| Summary: | <p><strong>Objective:</strong> to estimate the frequency and magnitude of acute kidney injury (AKI) in patients with acute decompensated chronic heart failure<br />(ADCHF) and to clarify the relationship of AKI to mortality.</p><p><br /><strong>Subjects and methods.</strong> One hundred and four patients (58 men and 46 women; mean age 65.3 ± 10.68 years) with ADCHF were examined.<br />AKI was diagnosed and classified by the KDIGO criteria.</p><p><br /><strong>Results.</strong> In terms of creatinine, AKI was diagnosed in 74 (71 %) patients (Stage I in 51 (49 %), Stage II in 20 (19 %), and Stage III in 3 (3 %)<br />patients. Five (5 %) patients died during hospitalization. All the dead patients had AKI. Multivariate regression analysis demonstrated that regardless of gender, age, chronic heart failure stage, the in-hospital mortality was associated with the level of creatinine (R = 0.29; β = 0.20;<br />p = 0.046). At the same time, in the patients with AKI Stages II-III the probability of in-hospital mortality was higher than that in the other patients (relative risk, 23.4; 95 % confidence interval 2.9–187.0; p = 0.003).</p><p><br /><strong>Conclusion.</strong> More than half of the patients with ADCHF have AKI according to the KRIGO criteria. The in-hospital mortality is much higher<br />amongst the patients with AKI Stages II-III.</p>
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