Skipping breakfast during pregnancy and hypertensive disorders of pregnancy in Japanese women: the Tohoku medical megabank project birth and three-generation cohort study
Abstract Background Hypertensive disorders of pregnancy (HDP) adversely affect the prognosis of mother and child, and the prognosis depends on the subtype of HDP. Skipping breakfast may be associated with increased blood pressure due to disruption of the circadian clock, but the association with the...
| Main Authors: | , , , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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BMC
2022-11-01
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| Series: | Nutrition Journal |
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| Online Access: | https://doi.org/10.1186/s12937-022-00822-9 |
| _version_ | 1811217732399529984 |
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| author | Misato Aizawa Keiko Murakami Ippei Takahashi Tomomi Onuma Aoi Noda Fumihiko Ueno Fumiko Matsuzaki Mami Ishikuro Taku Obara Hirotaka Hamada Noriyuki Iwama Masatoshi Saito Junichi Sugawara Nobuo Yaegashi Shinichi Kuriyama |
| author_facet | Misato Aizawa Keiko Murakami Ippei Takahashi Tomomi Onuma Aoi Noda Fumihiko Ueno Fumiko Matsuzaki Mami Ishikuro Taku Obara Hirotaka Hamada Noriyuki Iwama Masatoshi Saito Junichi Sugawara Nobuo Yaegashi Shinichi Kuriyama |
| author_sort | Misato Aizawa |
| collection | DOAJ |
| description | Abstract Background Hypertensive disorders of pregnancy (HDP) adversely affect the prognosis of mother and child, and the prognosis depends on the subtype of HDP. Skipping breakfast may be associated with increased blood pressure due to disruption of the circadian clock, but the association with the development of HDP has not been studied. The purpose of this study was to examine the association between skipping breakfast and the development of HDP and HDP subtypes in Japanese pregnant women. Methods Of the pregnant women who participated in the Tohoku Medical Megabank Project Three-Generation Cohort Study, 18,839 who answered the required questions were included in the analysis. This study had a cross-sectional design. The breakfast intake frequency from pre-pregnancy to early pregnancy was classified into four groups: daily, 5–6 times per week, 3–4 times per week, and 0–2 times per week. HDP was classified into gestational hypertension (GH), chronic hypertension (CH), preeclampsia (PE), and severe preeclampsia (SuPE). Multiple logistic regression analysis and multinomial logistic analysis were used to calculate odds ratios (ORs) and 95% confidence intervals (CIs) for breakfast intake frequency and development of HDP or HDP subtypes. We performed a stratified analysis based on energy intake. Results Of the participants, 74.3% consumed breakfast daily, and 11.1% developed HDP. Women who consumed breakfast 0–2 times per week had a higher risk of HDP (OR: 1.33, 95% CI: 1.14–1.56), CH (OR: 1.63, 95% CI: 1.21–2.19), and PE (OR: 1.68, 95% CI: 1.27–2.21) than those who consumed breakfast daily. No association was found between skipping breakfast and the risk of developing GH (OR: 1.26, 95% CI: 0.99–1.61) and SuPE (OR: 0.91, 95% CI: 0.55–1.49). Stratified analysis showed that the risk of developing HDP due to skipping breakfast was highest in the group with the highest daily energy intake. Conclusions Skipping breakfast during pre-to early pregnancy is associated with the development of HDP. Further longitudinal studies are required to clarify the causal association between skipping breakfast and HDP. |
| first_indexed | 2024-04-12T06:59:34Z |
| format | Article |
| id | doaj.art-c903e123be914931b31af2c73afdf1ce |
| institution | Directory Open Access Journal |
| issn | 1475-2891 |
| language | English |
| last_indexed | 2024-04-12T06:59:34Z |
| publishDate | 2022-11-01 |
| publisher | BMC |
| record_format | Article |
| series | Nutrition Journal |
| spelling | doaj.art-c903e123be914931b31af2c73afdf1ce2022-12-22T03:43:03ZengBMCNutrition Journal1475-28912022-11-0121111010.1186/s12937-022-00822-9Skipping breakfast during pregnancy and hypertensive disorders of pregnancy in Japanese women: the Tohoku medical megabank project birth and three-generation cohort studyMisato Aizawa0Keiko Murakami1Ippei Takahashi2Tomomi Onuma3Aoi Noda4Fumihiko Ueno5Fumiko Matsuzaki6Mami Ishikuro7Taku Obara8Hirotaka Hamada9Noriyuki Iwama10Masatoshi Saito11Junichi Sugawara12Nobuo Yaegashi13Shinichi Kuriyama14Graduate School of Medicine, Tohoku UniversityGraduate School of Medicine, Tohoku UniversityGraduate School of Medicine, Tohoku UniversityTohoku Medical Megabank Organization, Tohoku UniversityGraduate School of Medicine, Tohoku UniversityGraduate School of Medicine, Tohoku UniversityGraduate School of Medicine, Tohoku UniversityGraduate School of Medicine, Tohoku UniversityGraduate School of Medicine, Tohoku UniversityGraduate School of Medicine, Tohoku UniversityGraduate School of Medicine, Tohoku UniversityGraduate School of Medicine, Tohoku UniversityGraduate School of Medicine, Tohoku UniversityGraduate School of Medicine, Tohoku UniversityGraduate School of Medicine, Tohoku UniversityAbstract Background Hypertensive disorders of pregnancy (HDP) adversely affect the prognosis of mother and child, and the prognosis depends on the subtype of HDP. Skipping breakfast may be associated with increased blood pressure due to disruption of the circadian clock, but the association with the development of HDP has not been studied. The purpose of this study was to examine the association between skipping breakfast and the development of HDP and HDP subtypes in Japanese pregnant women. Methods Of the pregnant women who participated in the Tohoku Medical Megabank Project Three-Generation Cohort Study, 18,839 who answered the required questions were included in the analysis. This study had a cross-sectional design. The breakfast intake frequency from pre-pregnancy to early pregnancy was classified into four groups: daily, 5–6 times per week, 3–4 times per week, and 0–2 times per week. HDP was classified into gestational hypertension (GH), chronic hypertension (CH), preeclampsia (PE), and severe preeclampsia (SuPE). Multiple logistic regression analysis and multinomial logistic analysis were used to calculate odds ratios (ORs) and 95% confidence intervals (CIs) for breakfast intake frequency and development of HDP or HDP subtypes. We performed a stratified analysis based on energy intake. Results Of the participants, 74.3% consumed breakfast daily, and 11.1% developed HDP. Women who consumed breakfast 0–2 times per week had a higher risk of HDP (OR: 1.33, 95% CI: 1.14–1.56), CH (OR: 1.63, 95% CI: 1.21–2.19), and PE (OR: 1.68, 95% CI: 1.27–2.21) than those who consumed breakfast daily. No association was found between skipping breakfast and the risk of developing GH (OR: 1.26, 95% CI: 0.99–1.61) and SuPE (OR: 0.91, 95% CI: 0.55–1.49). Stratified analysis showed that the risk of developing HDP due to skipping breakfast was highest in the group with the highest daily energy intake. Conclusions Skipping breakfast during pre-to early pregnancy is associated with the development of HDP. Further longitudinal studies are required to clarify the causal association between skipping breakfast and HDP.https://doi.org/10.1186/s12937-022-00822-9Skipping breakfastHypertensive disorders of pregnancyPreeclampsiaJapanCircadian clock |
| spellingShingle | Misato Aizawa Keiko Murakami Ippei Takahashi Tomomi Onuma Aoi Noda Fumihiko Ueno Fumiko Matsuzaki Mami Ishikuro Taku Obara Hirotaka Hamada Noriyuki Iwama Masatoshi Saito Junichi Sugawara Nobuo Yaegashi Shinichi Kuriyama Skipping breakfast during pregnancy and hypertensive disorders of pregnancy in Japanese women: the Tohoku medical megabank project birth and three-generation cohort study Nutrition Journal Skipping breakfast Hypertensive disorders of pregnancy Preeclampsia Japan Circadian clock |
| title | Skipping breakfast during pregnancy and hypertensive disorders of pregnancy in Japanese women: the Tohoku medical megabank project birth and three-generation cohort study |
| title_full | Skipping breakfast during pregnancy and hypertensive disorders of pregnancy in Japanese women: the Tohoku medical megabank project birth and three-generation cohort study |
| title_fullStr | Skipping breakfast during pregnancy and hypertensive disorders of pregnancy in Japanese women: the Tohoku medical megabank project birth and three-generation cohort study |
| title_full_unstemmed | Skipping breakfast during pregnancy and hypertensive disorders of pregnancy in Japanese women: the Tohoku medical megabank project birth and three-generation cohort study |
| title_short | Skipping breakfast during pregnancy and hypertensive disorders of pregnancy in Japanese women: the Tohoku medical megabank project birth and three-generation cohort study |
| title_sort | skipping breakfast during pregnancy and hypertensive disorders of pregnancy in japanese women the tohoku medical megabank project birth and three generation cohort study |
| topic | Skipping breakfast Hypertensive disorders of pregnancy Preeclampsia Japan Circadian clock |
| url | https://doi.org/10.1186/s12937-022-00822-9 |
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