Dysregulation of the Tryptophan Pathway Evidences Gender Differences in COPD

Dysregulation of the Tryptophan Pathway Evidences Gender Differences in COPD

Increased activity of indoleamine 2,3-dioxygenase (IDO) and tryptophan hydroxylase (TPH) have been reported in individuals with chronic obstructive pulmonary disease (COPD). We therefore investigated the effect of gender stratification upon the observed levels of tryptophan metabolites in COPD. Tryp...

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Bibliographic Details
Main Authors: Shama Naz, Maria Bhat, Sara Ståhl, Helena Forsslund, C. Magnus Sköld, Åsa M. Wheelock, Craig E. Wheelock
Format: Article
Language:English
Published: MDPI AG 2019-10-01
Series:Metabolites
Subjects:
tryptophan
kynurenine
serotonin
gender
smoking
ido
copd
Online Access:https://www.mdpi.com/2218-1989/9/10/212

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