Phenotyping misophonia: Psychiatric disorders and medical health correlates

Misophonia is characterized by decreased tolerance to specific sounds and associated stimuli that causes significant psychological distress and impairment in daily functioning (Swedo et al., 2022). Aversive stimuli (often called “triggers”) are commonly repetitive facial (e.g., nose whistling, sniff...

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Main Authors: M. Zachary Rosenthal, Kibby McMahon, Anna S. Greenleaf, Clair Cassiello-Robbins, Rachel Guetta, Jacqueline Trumbull, Deepika Anand, Emily S. Frazer-Abel, Lisalynn Kelley
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-10-01
Series:Frontiers in Psychology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fpsyg.2022.941898/full
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author M. Zachary Rosenthal
M. Zachary Rosenthal
Kibby McMahon
Anna S. Greenleaf
Clair Cassiello-Robbins
Rachel Guetta
Jacqueline Trumbull
Deepika Anand
Emily S. Frazer-Abel
Lisalynn Kelley
author_facet M. Zachary Rosenthal
M. Zachary Rosenthal
Kibby McMahon
Anna S. Greenleaf
Clair Cassiello-Robbins
Rachel Guetta
Jacqueline Trumbull
Deepika Anand
Emily S. Frazer-Abel
Lisalynn Kelley
author_sort M. Zachary Rosenthal
collection DOAJ
description Misophonia is characterized by decreased tolerance to specific sounds and associated stimuli that causes significant psychological distress and impairment in daily functioning (Swedo et al., 2022). Aversive stimuli (often called “triggers”) are commonly repetitive facial (e.g., nose whistling, sniffling, and throat clearing) or oral (e.g., eating, drinking, and mouth breathing) sounds produced by other humans. Few empirical studies examining the nature and features of misophonia have used clinician-rated structured diagnostic interviews, and none have examined the relationship between misophonia and psychiatric disorders in the Diagnostic and Statistical Manual-5th version (DSM-5; American Psychiatric Association, 2013). In addition, little is known about whether there are any medical health problems associated with misophonia. Accordingly, the purpose of the present study was to improve the phenotypic characterization of misophonia by investigating the psychiatric and medical health correlates of this newly defined disorder. Structured diagnostic interviews were used to assess rates of lifetime and current DSM-5 psychiatric disorders in a community sample of 207 adults. The three most commonly diagnosed current psychiatric disorders were: (1) social anxiety disorder, (2) generalized anxiety disorder, and (3) specific phobia. The three most common lifetime psychiatric disorders were major depressive disorder, social anxiety disorder, and generalized anxiety disorder. A series of multiple regression analyses indicated that, among psychiatric disorders that were correlated with misophonia, those that remained significant predictors of misophonia severity after controlling for age and sex were borderline personality disorder, obsessive compulsive disorder, and panic disorder. No medical health problems were significantly positively correlated with misophonia severity.
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spelling doaj.art-c90c6ca6311e4779bd3738966af4d9952022-12-22T02:25:21ZengFrontiers Media S.A.Frontiers in Psychology1664-10782022-10-011310.3389/fpsyg.2022.941898941898Phenotyping misophonia: Psychiatric disorders and medical health correlatesM. Zachary Rosenthal0M. Zachary Rosenthal1Kibby McMahon2Anna S. Greenleaf3Clair Cassiello-Robbins4Rachel Guetta5Jacqueline Trumbull6Deepika Anand7Emily S. Frazer-Abel8Lisalynn Kelley9Department of Psychiatry and Behavior, Duke University Medical Center, Durham, NC, United StatesDepartment of Psychology and Neuroscience, Duke University, Durham, NC, United StatesDepartment of Psychiatry and Behavior, Duke University Medical Center, Durham, NC, United StatesDepartment of Psychology and Neuroscience, Duke University, Durham, NC, United StatesTriangle Area Psychology Clinic, Durham, NC, United StatesDepartment of Psychology and Neuroscience, Duke University, Durham, NC, United StatesDepartment of Psychology and Neuroscience, Duke University, Durham, NC, United StatesChicago Center for CBT, Chicago, IL, United StatesDepartment of Psychiatry and Behavior, Duke University Medical Center, Durham, NC, United StatesDepartment of Psychiatry and Behavior, Duke University Medical Center, Durham, NC, United StatesMisophonia is characterized by decreased tolerance to specific sounds and associated stimuli that causes significant psychological distress and impairment in daily functioning (Swedo et al., 2022). Aversive stimuli (often called “triggers”) are commonly repetitive facial (e.g., nose whistling, sniffling, and throat clearing) or oral (e.g., eating, drinking, and mouth breathing) sounds produced by other humans. Few empirical studies examining the nature and features of misophonia have used clinician-rated structured diagnostic interviews, and none have examined the relationship between misophonia and psychiatric disorders in the Diagnostic and Statistical Manual-5th version (DSM-5; American Psychiatric Association, 2013). In addition, little is known about whether there are any medical health problems associated with misophonia. Accordingly, the purpose of the present study was to improve the phenotypic characterization of misophonia by investigating the psychiatric and medical health correlates of this newly defined disorder. Structured diagnostic interviews were used to assess rates of lifetime and current DSM-5 psychiatric disorders in a community sample of 207 adults. The three most commonly diagnosed current psychiatric disorders were: (1) social anxiety disorder, (2) generalized anxiety disorder, and (3) specific phobia. The three most common lifetime psychiatric disorders were major depressive disorder, social anxiety disorder, and generalized anxiety disorder. A series of multiple regression analyses indicated that, among psychiatric disorders that were correlated with misophonia, those that remained significant predictors of misophonia severity after controlling for age and sex were borderline personality disorder, obsessive compulsive disorder, and panic disorder. No medical health problems were significantly positively correlated with misophonia severity.https://www.frontiersin.org/articles/10.3389/fpsyg.2022.941898/fullmisophoniamental healthmedical historypsychiatric disordersanxiety disorders
spellingShingle M. Zachary Rosenthal
M. Zachary Rosenthal
Kibby McMahon
Anna S. Greenleaf
Clair Cassiello-Robbins
Rachel Guetta
Jacqueline Trumbull
Deepika Anand
Emily S. Frazer-Abel
Lisalynn Kelley
Phenotyping misophonia: Psychiatric disorders and medical health correlates
Frontiers in Psychology
misophonia
mental health
medical history
psychiatric disorders
anxiety disorders
title Phenotyping misophonia: Psychiatric disorders and medical health correlates
title_full Phenotyping misophonia: Psychiatric disorders and medical health correlates
title_fullStr Phenotyping misophonia: Psychiatric disorders and medical health correlates
title_full_unstemmed Phenotyping misophonia: Psychiatric disorders and medical health correlates
title_short Phenotyping misophonia: Psychiatric disorders and medical health correlates
title_sort phenotyping misophonia psychiatric disorders and medical health correlates
topic misophonia
mental health
medical history
psychiatric disorders
anxiety disorders
url https://www.frontiersin.org/articles/10.3389/fpsyg.2022.941898/full
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