Kurarinone alleviates hemin‐induced neuroinflammation and microglia‐mediated neurotoxicity by shifting microglial M1/M2 polarization via regulating the IGF1/PI3K/Akt signaling
Abstract Cerebral hemorrhage is a fatal disease that causes severe damage to local nerve function. The purpose of this research is to analyze the effect of kurarinone on hemin‐induced neuroinflammation and neurotoxicity. In our study, according to the results of bioinformatics analysis, we hypothesi...
Main Authors: | Zeng‐Qiang Jia, Cheng Zuo, Wen‐Feng Yue |
---|---|
Format: | Article |
Language: | English |
Published: |
Wiley
2022-12-01
|
Series: | Kaohsiung Journal of Medical Sciences |
Subjects: | |
Online Access: | https://doi.org/10.1002/kjm2.12597 |
Similar Items
-
Neuroprotective effect of Kurarinone against corticosterone‐induced cytotoxicity on rat hippocampal neurons by targeting BACE1 to activate P13K–AKT signaling – A potential treatment in insomnia disorder
by: Guoqing Wu, et al.
Published: (2023-10-01) -
Anti-Inflammatory Activity of Kurarinone Involves Induction of HO-1 via the KEAP1/Nrf2 Pathway
by: Sakiko Nishikawa, et al.
Published: (2020-09-01) -
Kurarinone Attenuates BLM-Induced Pulmonary Fibrosis via Inhibiting TGF-β Signaling Pathways
by: Soo-Jin Park, et al.
Published: (2021-08-01) -
Kurarinone Attenuates Collagen-Induced Arthritis in Mice by Inhibiting Th1/Th17 Cell Responses and Oxidative Stress
by: Kuo-Tung Tang, et al.
Published: (2021-04-01) -
Kurarinone Inhibits HCoV-OC43 Infection by Impairing the Virus-Induced Autophagic Flux in MRC-5 Human Lung Cells
by: Jung Sun Min, et al.
Published: (2020-07-01)