Genomic data as the 'hitchhiker's guide' to cattle adaptation: tracking the milestones of past selection in the bovine genome
The bovine species have witnessed and played a major role in the drastic socio-economical changes that shaped our culture over the last 10,000 years. During this journey, cattle ‘hitchhiked’ on human development and colonized the world, facing strong selective pressures such as dramatic environmenta...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2015-02-01
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| Series: | Frontiers in Genetics |
| Subjects: | |
| Online Access: | http://journal.frontiersin.org/Journal/10.3389/fgene.2015.00036/full |
| _version_ | 1817995379023544320 |
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| author | Yuri Tani Utsunomiya Ana Maria Pérez O'Brien Tad Stewart Sonstegard Johann eSölkner Jose Fernando eGarcia |
| author_facet | Yuri Tani Utsunomiya Ana Maria Pérez O'Brien Tad Stewart Sonstegard Johann eSölkner Jose Fernando eGarcia |
| author_sort | Yuri Tani Utsunomiya |
| collection | DOAJ |
| description | The bovine species have witnessed and played a major role in the drastic socio-economical changes that shaped our culture over the last 10,000 years. During this journey, cattle ‘hitchhiked’ on human development and colonized the world, facing strong selective pressures such as dramatic environmental changes and disease challenge. Consequently, hundreds of specialized cattle breeds emerged and spread around the globe, making up a rich spectrum of genomic resources. Their DNA still carry the scars left from adapting to this wide range of conditions, and we are now empowered with data and analytical tools to track the milestones of past selection in their genomes. In this review paper, we provide a summary of the reconstructed demographic events that shaped cattle diversity, offer a critical synthesis of popular methodologies applied to the search for signatures of selection (SS) in genomic data, and give examples of recent SS studies in cattle. Then, we outline the potential and challenges of the application of SS analysis in cattle, and discuss the future directions in this field. |
| first_indexed | 2024-04-14T02:06:11Z |
| format | Article |
| id | doaj.art-c9150eacefa74063ac2ded32498741b0 |
| institution | Directory Open Access Journal |
| issn | 1664-8021 |
| language | English |
| last_indexed | 2024-04-14T02:06:11Z |
| publishDate | 2015-02-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Genetics |
| spelling | doaj.art-c9150eacefa74063ac2ded32498741b02022-12-22T02:18:41ZengFrontiers Media S.A.Frontiers in Genetics1664-80212015-02-01610.3389/fgene.2015.00036125042Genomic data as the 'hitchhiker's guide' to cattle adaptation: tracking the milestones of past selection in the bovine genomeYuri Tani Utsunomiya0Ana Maria Pérez O'Brien1Tad Stewart Sonstegard2Johann eSölkner3Jose Fernando eGarcia4Faculdade de Ciências Agrárias e Veterinárias, UNESP - Univ Estadual PaulistaBOKU - University of Natural Resources and Life SciencesARS-USDA - Agricultural Research Service - United States Department of AgricultureBOKU - University of Natural Resources and Life SciencesFaculdade de Medicina Veterinária de Araçatuba, UNESP - Univ Estadual PaulistaThe bovine species have witnessed and played a major role in the drastic socio-economical changes that shaped our culture over the last 10,000 years. During this journey, cattle ‘hitchhiked’ on human development and colonized the world, facing strong selective pressures such as dramatic environmental changes and disease challenge. Consequently, hundreds of specialized cattle breeds emerged and spread around the globe, making up a rich spectrum of genomic resources. Their DNA still carry the scars left from adapting to this wide range of conditions, and we are now empowered with data and analytical tools to track the milestones of past selection in their genomes. In this review paper, we provide a summary of the reconstructed demographic events that shaped cattle diversity, offer a critical synthesis of popular methodologies applied to the search for signatures of selection (SS) in genomic data, and give examples of recent SS studies in cattle. Then, we outline the potential and challenges of the application of SS analysis in cattle, and discuss the future directions in this field.http://journal.frontiersin.org/Journal/10.3389/fgene.2015.00036/fulladaptationSNPBos indicuspositive selectionBos taurus |
| spellingShingle | Yuri Tani Utsunomiya Ana Maria Pérez O'Brien Tad Stewart Sonstegard Johann eSölkner Jose Fernando eGarcia Genomic data as the 'hitchhiker's guide' to cattle adaptation: tracking the milestones of past selection in the bovine genome Frontiers in Genetics adaptation SNP Bos indicus positive selection Bos taurus |
| title | Genomic data as the 'hitchhiker's guide' to cattle adaptation: tracking the milestones of past selection in the bovine genome |
| title_full | Genomic data as the 'hitchhiker's guide' to cattle adaptation: tracking the milestones of past selection in the bovine genome |
| title_fullStr | Genomic data as the 'hitchhiker's guide' to cattle adaptation: tracking the milestones of past selection in the bovine genome |
| title_full_unstemmed | Genomic data as the 'hitchhiker's guide' to cattle adaptation: tracking the milestones of past selection in the bovine genome |
| title_short | Genomic data as the 'hitchhiker's guide' to cattle adaptation: tracking the milestones of past selection in the bovine genome |
| title_sort | genomic data as the 39 hitchhiker 39 s guide 39 to cattle adaptation tracking the milestones of past selection in the bovine genome |
| topic | adaptation SNP Bos indicus positive selection Bos taurus |
| url | http://journal.frontiersin.org/Journal/10.3389/fgene.2015.00036/full |
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