Primary hepatic adenosquamous carcinoma: A rare case report

Primary hepatic adenosquamous carcinoma (ASC) is an extremely rare primary hepatic malignant tumor, which is easily misdiagnosed as hepatocellular carcinoma before surgery. It has both the histologic features—adenocarcinoma and squamous cell carcinoma. Primary hepatic ASC incidence rate in intrahepa...

Full description

Bibliographic Details
Main Authors: Dong Wei, Liu Lu, Chen Ying, Kang Qingsong, Li Dongbo, Li Feibo
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2021-01-01
Series:Indian Journal of Pathology and Microbiology
Subjects:
Online Access:http://www.ijpmonline.org/article.asp?issn=0377-4929;year=2021;volume=64;issue=5;spage=140;epage=142;aulast=Wei
_version_ 1818573688280186880
author Dong Wei
Liu Lu
Chen Ying
Kang Qingsong
Li Dongbo
Li Feibo
author_facet Dong Wei
Liu Lu
Chen Ying
Kang Qingsong
Li Dongbo
Li Feibo
author_sort Dong Wei
collection DOAJ
description Primary hepatic adenosquamous carcinoma (ASC) is an extremely rare primary hepatic malignant tumor, which is easily misdiagnosed as hepatocellular carcinoma before surgery. It has both the histologic features—adenocarcinoma and squamous cell carcinoma. Primary hepatic ASC incidence rate in intrahepatic cholangiocarcinoma is 2% to 3%.[1] Patients with hepatic ASC may experience recurrence or metastasis after surgery. The epidemiology, clinical diagnosis, etiology, and treatment of the disease remain challenging. It is important to improve the recognition of hepatic ASC because of its bad prognosis. Here, we report a man who had complained of an upper stomachache for 2 months and was diagnosed with primary hepatic ASC by histology and immunohistochemistry (IHC) after laparoscopic hepatectomy. The patient remained asymptomatic and survived well for 2 years post surgery and long-term follow-up was continued till now. In addition, we offer a brief discussion about the histopathological features, clinical behavior, and treatment of hepatic ASC and review the relevant literature.
first_indexed 2024-12-15T00:14:57Z
format Article
id doaj.art-c9173a17728a462d91c8f2e0c106dd1d
institution Directory Open Access Journal
issn 0377-4929
language English
last_indexed 2024-12-15T00:14:57Z
publishDate 2021-01-01
publisher Wolters Kluwer Medknow Publications
record_format Article
series Indian Journal of Pathology and Microbiology
spelling doaj.art-c9173a17728a462d91c8f2e0c106dd1d2022-12-21T22:42:28ZengWolters Kluwer Medknow PublicationsIndian Journal of Pathology and Microbiology0377-49292021-01-0164514014210.4103/IJPM.IJPM_785_18Primary hepatic adenosquamous carcinoma: A rare case reportDong WeiLiu LuChen YingKang QingsongLi DongboLi FeiboPrimary hepatic adenosquamous carcinoma (ASC) is an extremely rare primary hepatic malignant tumor, which is easily misdiagnosed as hepatocellular carcinoma before surgery. It has both the histologic features—adenocarcinoma and squamous cell carcinoma. Primary hepatic ASC incidence rate in intrahepatic cholangiocarcinoma is 2% to 3%.[1] Patients with hepatic ASC may experience recurrence or metastasis after surgery. The epidemiology, clinical diagnosis, etiology, and treatment of the disease remain challenging. It is important to improve the recognition of hepatic ASC because of its bad prognosis. Here, we report a man who had complained of an upper stomachache for 2 months and was diagnosed with primary hepatic ASC by histology and immunohistochemistry (IHC) after laparoscopic hepatectomy. The patient remained asymptomatic and survived well for 2 years post surgery and long-term follow-up was continued till now. In addition, we offer a brief discussion about the histopathological features, clinical behavior, and treatment of hepatic ASC and review the relevant literature.http://www.ijpmonline.org/article.asp?issn=0377-4929;year=2021;volume=64;issue=5;spage=140;epage=142;aulast=Weiadenosquamous carcinomahepatic tumorimmunohistochemistrylaparoscopic hepatectomypathology
spellingShingle Dong Wei
Liu Lu
Chen Ying
Kang Qingsong
Li Dongbo
Li Feibo
Primary hepatic adenosquamous carcinoma: A rare case report
Indian Journal of Pathology and Microbiology
adenosquamous carcinoma
hepatic tumor
immunohistochemistry
laparoscopic hepatectomy
pathology
title Primary hepatic adenosquamous carcinoma: A rare case report
title_full Primary hepatic adenosquamous carcinoma: A rare case report
title_fullStr Primary hepatic adenosquamous carcinoma: A rare case report
title_full_unstemmed Primary hepatic adenosquamous carcinoma: A rare case report
title_short Primary hepatic adenosquamous carcinoma: A rare case report
title_sort primary hepatic adenosquamous carcinoma a rare case report
topic adenosquamous carcinoma
hepatic tumor
immunohistochemistry
laparoscopic hepatectomy
pathology
url http://www.ijpmonline.org/article.asp?issn=0377-4929;year=2021;volume=64;issue=5;spage=140;epage=142;aulast=Wei
work_keys_str_mv AT dongwei primaryhepaticadenosquamouscarcinomaararecasereport
AT liulu primaryhepaticadenosquamouscarcinomaararecasereport
AT chenying primaryhepaticadenosquamouscarcinomaararecasereport
AT kangqingsong primaryhepaticadenosquamouscarcinomaararecasereport
AT lidongbo primaryhepaticadenosquamouscarcinomaararecasereport
AT lifeibo primaryhepaticadenosquamouscarcinomaararecasereport