Tuberculous peritonitis mimicking carcinomatosis peritonei: CT findings and histopathologic correlation
The distinction between tuberculous peritonitis and peritoneal carcinomatosis is extremely difficult in patients with omental cake appearance on computed tomography and elevated CA-125 level. A 21-year-old female presented with abdominal distention, diarrhea, nausea, fever, weight loss, and night sw...
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| Format: | Article |
| Language: | English |
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Elsevier
2019-12-01
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| Series: | Radiology Case Reports |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1930043319303152 |
| _version_ | 1811207062730833920 |
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| author | Bülent Aslan, MD Davut Tüney, MD Zahra Abdulaziz N. Almoabid, MD Yiğit Erçetin, MD İpek Erbarut Seven |
| author_facet | Bülent Aslan, MD Davut Tüney, MD Zahra Abdulaziz N. Almoabid, MD Yiğit Erçetin, MD İpek Erbarut Seven |
| author_sort | Bülent Aslan, MD |
| collection | DOAJ |
| description | The distinction between tuberculous peritonitis and peritoneal carcinomatosis is extremely difficult in patients with omental cake appearance on computed tomography and elevated CA-125 level. A 21-year-old female presented with abdominal distention, diarrhea, nausea, fever, weight loss, and night sweats. Serum CA-125 level was 563 U/L (normal range: <35 U/L) and other tumor markers were within normal range. Radiologic studies showed massive ascites, smooth minimal thickening and increased contrast enhancement of peritoneum, omental nodularities, hepatomegaly, and right pleural effusion. No underlying malignancy that could cause this condition was detected clinically and radiologically. Ultrasound-guided omental tru-cut biopsy was performed to exclude carcinomatosis peritonei. Histopathologic examination showed small-medium-sized granulomas with caseous necrosis. Molecular microbiology tests of biopsy specimens confirmed diagnosis of tuberculosis. In conclusion, tuberculous peritonitis should be in differential diagnosis of a patient with ascites, omental nodularities and elevated serum CA-125 levels. Keywords: Carcinomatosis peritonei, Computed tomography (CT), Tuberculous peritonitis, Ovarian cancer, CA-125 |
| first_indexed | 2024-04-12T03:58:44Z |
| format | Article |
| id | doaj.art-c918773705a14f95b744590d206c0da2 |
| institution | Directory Open Access Journal |
| issn | 1930-0433 |
| language | English |
| last_indexed | 2024-04-12T03:58:44Z |
| publishDate | 2019-12-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Radiology Case Reports |
| spelling | doaj.art-c918773705a14f95b744590d206c0da22022-12-22T03:48:46ZengElsevierRadiology Case Reports1930-04332019-12-01141214911494Tuberculous peritonitis mimicking carcinomatosis peritonei: CT findings and histopathologic correlationBülent Aslan, MD0Davut Tüney, MD1Zahra Abdulaziz N. Almoabid, MD2Yiğit Erçetin, MD3İpek Erbarut Seven4Department of Radiology, Hospital of Marmara University School of Medicine, Istanbul, Turkey; Corresponding author.Department of Radiology, Hospital of Marmara University School of Medicine, Istanbul, TurkeyHospital of Marmara University School of Medicine, Istanbul, TurkeyDepartment of Pathology, Hospital of Marmara University School of Medicine, Istanbul, TurkeyDepartment of Pathology, Hospital of Marmara University School of Medicine, Istanbul, TurkeyThe distinction between tuberculous peritonitis and peritoneal carcinomatosis is extremely difficult in patients with omental cake appearance on computed tomography and elevated CA-125 level. A 21-year-old female presented with abdominal distention, diarrhea, nausea, fever, weight loss, and night sweats. Serum CA-125 level was 563 U/L (normal range: <35 U/L) and other tumor markers were within normal range. Radiologic studies showed massive ascites, smooth minimal thickening and increased contrast enhancement of peritoneum, omental nodularities, hepatomegaly, and right pleural effusion. No underlying malignancy that could cause this condition was detected clinically and radiologically. Ultrasound-guided omental tru-cut biopsy was performed to exclude carcinomatosis peritonei. Histopathologic examination showed small-medium-sized granulomas with caseous necrosis. Molecular microbiology tests of biopsy specimens confirmed diagnosis of tuberculosis. In conclusion, tuberculous peritonitis should be in differential diagnosis of a patient with ascites, omental nodularities and elevated serum CA-125 levels. Keywords: Carcinomatosis peritonei, Computed tomography (CT), Tuberculous peritonitis, Ovarian cancer, CA-125http://www.sciencedirect.com/science/article/pii/S1930043319303152 |
| spellingShingle | Bülent Aslan, MD Davut Tüney, MD Zahra Abdulaziz N. Almoabid, MD Yiğit Erçetin, MD İpek Erbarut Seven Tuberculous peritonitis mimicking carcinomatosis peritonei: CT findings and histopathologic correlation Radiology Case Reports |
| title | Tuberculous peritonitis mimicking carcinomatosis peritonei: CT findings and histopathologic correlation |
| title_full | Tuberculous peritonitis mimicking carcinomatosis peritonei: CT findings and histopathologic correlation |
| title_fullStr | Tuberculous peritonitis mimicking carcinomatosis peritonei: CT findings and histopathologic correlation |
| title_full_unstemmed | Tuberculous peritonitis mimicking carcinomatosis peritonei: CT findings and histopathologic correlation |
| title_short | Tuberculous peritonitis mimicking carcinomatosis peritonei: CT findings and histopathologic correlation |
| title_sort | tuberculous peritonitis mimicking carcinomatosis peritonei ct findings and histopathologic correlation |
| url | http://www.sciencedirect.com/science/article/pii/S1930043319303152 |
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