The Decrease in Estimated Glomerular Filtration Rate as a Risk Factor of Ventricular Tachyarrhythmias after Acute Myocardial Infarction during Hospitalization: A Retrospective Propensity Score Matching Cohort Study
Background: To identify the decrease in estimated glomerular filtration rate (eGFR) as an independent risk factor associated with ventricular tachyarrhythmias (VTA). Methods: This retrospective file review collected information from patients diagnosed with acute myocardial infarction (AMI), with and...
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| Format: | Article |
| Language: | English |
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IMR Press
2024-01-01
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| Series: | Reviews in Cardiovascular Medicine |
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| Online Access: | https://www.imrpress.com/journal/RCM/25/2/10.31083/j.rcm2502042 |
| _version_ | 1797291661844283392 |
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| author | Ming Li Chongzhou Zheng Chunmei Chen Xifeng Zheng Zhongkai He |
| author_facet | Ming Li Chongzhou Zheng Chunmei Chen Xifeng Zheng Zhongkai He |
| author_sort | Ming Li |
| collection | DOAJ |
| description | Background: To identify the decrease in estimated glomerular filtration rate (eGFR) as an independent risk factor associated with ventricular tachyarrhythmias (VTA). Methods: This retrospective file review collected information from patients diagnosed with acute myocardial infarction (AMI), with and without VTA, from January 2017 to December 2019. We first applied the chi-square test to assess 12 risk factors and one outcome variable (incident rate of VTA). Next, all the 12 risk factors were further adjusted using the propensity score matching (PSM) method to simulate the dataset as a randomized controlled cohort, which can reduce the defects derived from confounding factors and the imbalance in baseline characteristics. To investigate the relationship between eGFR and VTA, univariate logistic regression analysis was applied to the cohort before and after PSM analysis. Results: A total of 503 patients diagnosed as AMI were included in the study. There were eight of twelve risk factors in baseline characteristics with a p-value < 0.05, as determined by the chi-square test before PSM matching. The result of PSM analysis indicated that 86 of 91 patients with decreased eGFR were matched, and all the risk factors were not significantly different (p-value > 0.05). The incident rates of VTA in the two groups were still significantly different (p-value < 0.001) according to the Pearson chi-square test in the cohort after PSM analysis. The results of univariate (eGFR) logistic regression indicated that the odds ratio of the cohort was 6.442 (95% confidence interval = 3.770–11.05) and 3.654 (95% confidence interval = 1.764–7.993) before and after PSM analysis respectively. Conclusions: The decrease in eGFR (<60 mL/min/1.73 m2) has been demonstrated as an independent risk factor for VTA after AMI. |
| first_indexed | 2024-03-07T19:39:37Z |
| format | Article |
| id | doaj.art-c91cddf388bf4eaea63c57b3711d245b |
| institution | Directory Open Access Journal |
| issn | 1530-6550 |
| language | English |
| last_indexed | 2024-03-07T19:39:37Z |
| publishDate | 2024-01-01 |
| publisher | IMR Press |
| record_format | Article |
| series | Reviews in Cardiovascular Medicine |
| spelling | doaj.art-c91cddf388bf4eaea63c57b3711d245b2024-02-29T06:14:30ZengIMR PressReviews in Cardiovascular Medicine1530-65502024-01-012524210.31083/j.rcm2502042S1530-6550(23)01225-5The Decrease in Estimated Glomerular Filtration Rate as a Risk Factor of Ventricular Tachyarrhythmias after Acute Myocardial Infarction during Hospitalization: A Retrospective Propensity Score Matching Cohort StudyMing Li0Chongzhou Zheng1Chunmei Chen2Xifeng Zheng3Zhongkai He4Department of Cardiology, Affiliated Hospital of Guangdong Medical University, 524001 Zhanjiang, Guangdong, ChinaDepartment of Cardiology, Affiliated Hospital of Guangdong Medical University, 524001 Zhanjiang, Guangdong, ChinaDepartment of Cardiology, Affiliated Hospital of Guangdong Medical University, 524001 Zhanjiang, Guangdong, ChinaDepartment of Cardiology, Affiliated Hospital of Guangdong Medical University, 524001 Zhanjiang, Guangdong, ChinaDepartment of Cardiology, Affiliated Hospital of Guangdong Medical University, 524001 Zhanjiang, Guangdong, ChinaBackground: To identify the decrease in estimated glomerular filtration rate (eGFR) as an independent risk factor associated with ventricular tachyarrhythmias (VTA). Methods: This retrospective file review collected information from patients diagnosed with acute myocardial infarction (AMI), with and without VTA, from January 2017 to December 2019. We first applied the chi-square test to assess 12 risk factors and one outcome variable (incident rate of VTA). Next, all the 12 risk factors were further adjusted using the propensity score matching (PSM) method to simulate the dataset as a randomized controlled cohort, which can reduce the defects derived from confounding factors and the imbalance in baseline characteristics. To investigate the relationship between eGFR and VTA, univariate logistic regression analysis was applied to the cohort before and after PSM analysis. Results: A total of 503 patients diagnosed as AMI were included in the study. There were eight of twelve risk factors in baseline characteristics with a p-value < 0.05, as determined by the chi-square test before PSM matching. The result of PSM analysis indicated that 86 of 91 patients with decreased eGFR were matched, and all the risk factors were not significantly different (p-value > 0.05). The incident rates of VTA in the two groups were still significantly different (p-value < 0.001) according to the Pearson chi-square test in the cohort after PSM analysis. The results of univariate (eGFR) logistic regression indicated that the odds ratio of the cohort was 6.442 (95% confidence interval = 3.770–11.05) and 3.654 (95% confidence interval = 1.764–7.993) before and after PSM analysis respectively. Conclusions: The decrease in eGFR (<60 mL/min/1.73 m2) has been demonstrated as an independent risk factor for VTA after AMI.https://www.imrpress.com/journal/RCM/25/2/10.31083/j.rcm2502042estimated glomerular filtration rateventricular tachycardiaacute myocardial infarctionpropensity score matching |
| spellingShingle | Ming Li Chongzhou Zheng Chunmei Chen Xifeng Zheng Zhongkai He The Decrease in Estimated Glomerular Filtration Rate as a Risk Factor of Ventricular Tachyarrhythmias after Acute Myocardial Infarction during Hospitalization: A Retrospective Propensity Score Matching Cohort Study Reviews in Cardiovascular Medicine estimated glomerular filtration rate ventricular tachycardia acute myocardial infarction propensity score matching |
| title | The Decrease in Estimated Glomerular Filtration Rate as a Risk Factor of Ventricular Tachyarrhythmias after Acute Myocardial Infarction during Hospitalization: A Retrospective Propensity Score Matching Cohort Study |
| title_full | The Decrease in Estimated Glomerular Filtration Rate as a Risk Factor of Ventricular Tachyarrhythmias after Acute Myocardial Infarction during Hospitalization: A Retrospective Propensity Score Matching Cohort Study |
| title_fullStr | The Decrease in Estimated Glomerular Filtration Rate as a Risk Factor of Ventricular Tachyarrhythmias after Acute Myocardial Infarction during Hospitalization: A Retrospective Propensity Score Matching Cohort Study |
| title_full_unstemmed | The Decrease in Estimated Glomerular Filtration Rate as a Risk Factor of Ventricular Tachyarrhythmias after Acute Myocardial Infarction during Hospitalization: A Retrospective Propensity Score Matching Cohort Study |
| title_short | The Decrease in Estimated Glomerular Filtration Rate as a Risk Factor of Ventricular Tachyarrhythmias after Acute Myocardial Infarction during Hospitalization: A Retrospective Propensity Score Matching Cohort Study |
| title_sort | decrease in estimated glomerular filtration rate as a risk factor of ventricular tachyarrhythmias after acute myocardial infarction during hospitalization a retrospective propensity score matching cohort study |
| topic | estimated glomerular filtration rate ventricular tachycardia acute myocardial infarction propensity score matching |
| url | https://www.imrpress.com/journal/RCM/25/2/10.31083/j.rcm2502042 |
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