Virilizing adrenocortical carcinoma in a child: A rare enigma
Adrenocortical carcinomas are rare tumors with an incidence of one to two cases per million population and are still more rarer in the pediatric age group. Adrenocortical carcinomas can be functional or may be unassociated with syndromes of hormone overproduction. It is very important to differentia...
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Format: | Article |
Language: | English |
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Wolters Kluwer Medknow Publications
2012-01-01
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Series: | Indian Journal of Endocrinology and Metabolism |
Subjects: | |
Online Access: | http://www.ijem.in/article.asp?issn=2230-8210;year=2012;volume=16;issue=4;spage=621;epage=623;aulast=Sipayya |
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author | Varuna Sipayya Yogesh K Yadav Rashmi Arora Uma Sharma Kusum Gupta |
author_facet | Varuna Sipayya Yogesh K Yadav Rashmi Arora Uma Sharma Kusum Gupta |
author_sort | Varuna Sipayya |
collection | DOAJ |
description | Adrenocortical carcinomas are rare tumors with an incidence of one to two cases per million population and are still more rarer in the pediatric age group. Adrenocortical carcinomas can be functional or may be unassociated with syndromes of hormone overproduction. It is very important to differentiate an adrenocortical adenoma from a carcinoma, as both share a large number of phenotypic features, and assess their prognosis, as adrenocortical carcinoma may need an adjuvant therapy. In this communication, we describe the case of a two-year-old boy, who presented with iso-sexual precocious puberty, having features of virilization, which included growth of facial and pubic hair, deepening of voice, and penile growth. |
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format | Article |
id | doaj.art-c91eefa4869a40eaa8e75250308c1cd5 |
institution | Directory Open Access Journal |
issn | 2230-8210 2230-9500 |
language | English |
last_indexed | 2024-12-21T02:46:21Z |
publishDate | 2012-01-01 |
publisher | Wolters Kluwer Medknow Publications |
record_format | Article |
series | Indian Journal of Endocrinology and Metabolism |
spelling | doaj.art-c91eefa4869a40eaa8e75250308c1cd52022-12-21T19:18:33ZengWolters Kluwer Medknow PublicationsIndian Journal of Endocrinology and Metabolism2230-82102230-95002012-01-0116462162310.4103/2230-8210.98025Virilizing adrenocortical carcinoma in a child: A rare enigmaVaruna SipayyaYogesh K YadavRashmi AroraUma SharmaKusum GuptaAdrenocortical carcinomas are rare tumors with an incidence of one to two cases per million population and are still more rarer in the pediatric age group. Adrenocortical carcinomas can be functional or may be unassociated with syndromes of hormone overproduction. It is very important to differentiate an adrenocortical adenoma from a carcinoma, as both share a large number of phenotypic features, and assess their prognosis, as adrenocortical carcinoma may need an adjuvant therapy. In this communication, we describe the case of a two-year-old boy, who presented with iso-sexual precocious puberty, having features of virilization, which included growth of facial and pubic hair, deepening of voice, and penile growth.http://www.ijem.in/article.asp?issn=2230-8210;year=2012;volume=16;issue=4;spage=621;epage=623;aulast=SipayyaAdrenocortical tumorvirilizationWeiss criteria |
spellingShingle | Varuna Sipayya Yogesh K Yadav Rashmi Arora Uma Sharma Kusum Gupta Virilizing adrenocortical carcinoma in a child: A rare enigma Indian Journal of Endocrinology and Metabolism Adrenocortical tumor virilization Weiss criteria |
title | Virilizing adrenocortical carcinoma in a child: A rare enigma |
title_full | Virilizing adrenocortical carcinoma in a child: A rare enigma |
title_fullStr | Virilizing adrenocortical carcinoma in a child: A rare enigma |
title_full_unstemmed | Virilizing adrenocortical carcinoma in a child: A rare enigma |
title_short | Virilizing adrenocortical carcinoma in a child: A rare enigma |
title_sort | virilizing adrenocortical carcinoma in a child a rare enigma |
topic | Adrenocortical tumor virilization Weiss criteria |
url | http://www.ijem.in/article.asp?issn=2230-8210;year=2012;volume=16;issue=4;spage=621;epage=623;aulast=Sipayya |
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