Virilizing adrenocortical carcinoma in a child: A rare enigma

Adrenocortical carcinomas are rare tumors with an incidence of one to two cases per million population and are still more rarer in the pediatric age group. Adrenocortical carcinomas can be functional or may be unassociated with syndromes of hormone overproduction. It is very important to differentia...

Full description

Bibliographic Details
Main Authors: Varuna Sipayya, Yogesh K Yadav, Rashmi Arora, Uma Sharma, Kusum Gupta
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2012-01-01
Series:Indian Journal of Endocrinology and Metabolism
Subjects:
Online Access:http://www.ijem.in/article.asp?issn=2230-8210;year=2012;volume=16;issue=4;spage=621;epage=623;aulast=Sipayya
_version_ 1819016357783535616
author Varuna Sipayya
Yogesh K Yadav
Rashmi Arora
Uma Sharma
Kusum Gupta
author_facet Varuna Sipayya
Yogesh K Yadav
Rashmi Arora
Uma Sharma
Kusum Gupta
author_sort Varuna Sipayya
collection DOAJ
description Adrenocortical carcinomas are rare tumors with an incidence of one to two cases per million population and are still more rarer in the pediatric age group. Adrenocortical carcinomas can be functional or may be unassociated with syndromes of hormone overproduction. It is very important to differentiate an adrenocortical adenoma from a carcinoma, as both share a large number of phenotypic features, and assess their prognosis, as adrenocortical carcinoma may need an adjuvant therapy. In this communication, we describe the case of a two-year-old boy, who presented with iso-sexual precocious puberty, having features of virilization, which included growth of facial and pubic hair, deepening of voice, and penile growth.
first_indexed 2024-12-21T02:46:21Z
format Article
id doaj.art-c91eefa4869a40eaa8e75250308c1cd5
institution Directory Open Access Journal
issn 2230-8210
2230-9500
language English
last_indexed 2024-12-21T02:46:21Z
publishDate 2012-01-01
publisher Wolters Kluwer Medknow Publications
record_format Article
series Indian Journal of Endocrinology and Metabolism
spelling doaj.art-c91eefa4869a40eaa8e75250308c1cd52022-12-21T19:18:33ZengWolters Kluwer Medknow PublicationsIndian Journal of Endocrinology and Metabolism2230-82102230-95002012-01-0116462162310.4103/2230-8210.98025Virilizing adrenocortical carcinoma in a child: A rare enigmaVaruna SipayyaYogesh K YadavRashmi AroraUma SharmaKusum GuptaAdrenocortical carcinomas are rare tumors with an incidence of one to two cases per million population and are still more rarer in the pediatric age group. Adrenocortical carcinomas can be functional or may be unassociated with syndromes of hormone overproduction. It is very important to differentiate an adrenocortical adenoma from a carcinoma, as both share a large number of phenotypic features, and assess their prognosis, as adrenocortical carcinoma may need an adjuvant therapy. In this communication, we describe the case of a two-year-old boy, who presented with iso-sexual precocious puberty, having features of virilization, which included growth of facial and pubic hair, deepening of voice, and penile growth.http://www.ijem.in/article.asp?issn=2230-8210;year=2012;volume=16;issue=4;spage=621;epage=623;aulast=SipayyaAdrenocortical tumorvirilizationWeiss criteria
spellingShingle Varuna Sipayya
Yogesh K Yadav
Rashmi Arora
Uma Sharma
Kusum Gupta
Virilizing adrenocortical carcinoma in a child: A rare enigma
Indian Journal of Endocrinology and Metabolism
Adrenocortical tumor
virilization
Weiss criteria
title Virilizing adrenocortical carcinoma in a child: A rare enigma
title_full Virilizing adrenocortical carcinoma in a child: A rare enigma
title_fullStr Virilizing adrenocortical carcinoma in a child: A rare enigma
title_full_unstemmed Virilizing adrenocortical carcinoma in a child: A rare enigma
title_short Virilizing adrenocortical carcinoma in a child: A rare enigma
title_sort virilizing adrenocortical carcinoma in a child a rare enigma
topic Adrenocortical tumor
virilization
Weiss criteria
url http://www.ijem.in/article.asp?issn=2230-8210;year=2012;volume=16;issue=4;spage=621;epage=623;aulast=Sipayya
work_keys_str_mv AT varunasipayya virilizingadrenocorticalcarcinomainachildarareenigma
AT yogeshkyadav virilizingadrenocorticalcarcinomainachildarareenigma
AT rashmiarora virilizingadrenocorticalcarcinomainachildarareenigma
AT umasharma virilizingadrenocorticalcarcinomainachildarareenigma
AT kusumgupta virilizingadrenocorticalcarcinomainachildarareenigma