Wg/Wnt1 and Erasp link ER stress to proapoptotic signaling in an autosomal dominant retinitis pigmentosa model

Abstract The endoplasmic reticulum (ER) is a subcellular organelle essential for cellular homeostasis. Perturbation of ER functions due to various conditions can induce apoptosis. Chronic ER stress has been implicated in a wide range of diseases, including autosomal dominant retinitis pigmentosa (AD...

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Bibliographic Details
Main Authors: Jung-Eun Park, Jiyoun Lee, Soonhyuck Ok, Seunghee Byun, Eun-Ju Chang, Sung-Eun Yoon, Young-Joon Kim, Min-Ji Kang
Format: Article
Language:English
Published: Nature Publishing Group 2023-07-01
Series:Experimental and Molecular Medicine
Online Access:https://doi.org/10.1038/s12276-023-01044-7