Peptic Ulcer Disease Different Pathogenesis of Duodenal and Gastric Ulcer

Despite decrease frequency of Helicobacter pylori (H. pylori) due to eradication therapy, peptic ulcer disease as a manifestation of this infection is still remain a health burden. Understanding the physiology of gastric acid secretion and its alteration by H. pylori induced inflammation will aid ph...

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Bibliographic Details
Main Authors: Hendra Koncoro, I Dewa Nyoman Wibawa
Format: Article
Language:English
Published: Interna Publishing 2015-12-01
Series:The Indonesian Journal of Gastroenterology, Hepatology and Digestive Endoscopy
Subjects:
Online Access:http://ina-jghe.com/journal/index.php/jghe/article/view/501/427
Description
Summary:Despite decrease frequency of Helicobacter pylori (H. pylori) due to eradication therapy, peptic ulcer disease as a manifestation of this infection is still remain a health burden. Understanding the physiology of gastric acid secretion and its alteration by H. pylori induced inflammation will aid physician in differentiating peptic ulcer disease based on its location. Duodenal ulcer and gastric ulcer disease are two common condition that usually found in peptic ulcer. Recognition of symptoms and its pathogenesis may lead physician to understand the fate of each condition in the future. This article reviews concept of peptic ulcer pathogenesis according to ulcer etiology.
ISSN:1411-4801
2302-8181