Does Deoxynivalenol Affect Amoxicillin and Doxycycline Absorption in the Gastrointestinal Tract? Ex Vivo Study on Swine Jejunum Mucosa Explants

Does Deoxynivalenol Affect Amoxicillin and Doxycycline Absorption in the Gastrointestinal Tract? Ex Vivo Study on Swine Jejunum Mucosa Explants

The presence of deoxynivalenol (DON) in feed may increase intestinal barrier permeability. Disturbance of the intestinal barrier integrity may affect the absorption of antibiotics used in animals. Since the bioavailability of orally administered antibiotics significantly affects their efficacy and s...

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Bibliographic Details
Main Authors: Marta Mendel, Wojciech Karlik, Urszula Latek, Magdalena Chłopecka, Ewelina Nowacka-Kozak, Katarzyna Pietruszka, Piotr Jedziniak
Format: Article
Language:English
Published: MDPI AG 2022-10-01
Series:Toxins
Subjects:
deoxynivalenol
amoxicillin
doxycycline
Ussing chamber
swine jejunum mucosa explants
Online Access:https://www.mdpi.com/2072-6651/14/11/743

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