Pharmacological and Structure-Activity Relationship Evaluation of 4-aryl-1-Diphenylacetyl(thio)semicarbazides

Pharmacological and Structure-Activity Relationship Evaluation of 4-aryl-1-Diphenylacetyl(thio)semicarbazides

This article describes the synthesis of six 4-aryl-(thio)semicarbazides (series a and b) linked with diphenylacetyl moiety along with their pharmacological evaluation on the central nervous system in mice and computational studies, including conformational analysis and electrostatic properties. All...

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Chi tiết về thư mục
Những tác giả chính: Monika Wujec, Ewa Kędzierska, Edyta Kuśmierz, Tomasz Plech, Andrzej Wróbel, Agata Paneth, Jolanta Orzelska, Sylwia Fidecka, Piotr Paneth
Định dạng: Bài viết
Ngôn ngữ:English
Được phát hành: MDPI AG 2014-04-01
Loạt:Molecules
Những chủ đề:
(thio)semicarbazides
conformational analysis
electrostatic properties
CNS activity
analgesic activity
serotonergic activity
Truy cập trực tuyến:http://www.mdpi.com/1420-3049/19/4/4745

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http://www.mdpi.com/1420-3049/19/4/4745

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